54833-61-3 Usage
General Description
2,4-Imidazolidinedione, 5-(4-methoxyphenyl)-3-methyl-5-phenyl- is a chemical compound that is also known as Phenobarbital. It is a barbiturate medication that is commonly used as an anticonvulsant and sedative. Phenobarbital works by enhancing the activity of the neurotransmitter gamma-aminobutyric acid (GABA) in the brain, leading to a calming effect on the central nervous system. It is often prescribed to treat seizures, anxiety, and as a sedative for surgery or other medical procedures. However, it also has a potential for abuse and dependence, and its use should be closely monitored by healthcare professionals. Additionally, Phenobarbital has been listed as an essential medicine by the World Health Organization due to its effectiveness and safety when used appropriately.
Check Digit Verification of cas no
The CAS Registry Mumber 54833-61-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,8,3 and 3 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 54833-61:
(7*5)+(6*4)+(5*8)+(4*3)+(3*3)+(2*6)+(1*1)=133
133 % 10 = 3
So 54833-61-3 is a valid CAS Registry Number.
InChI:InChI=1/C17H16N2O3/c1-19-15(20)17(18-16(19)21,12-6-4-3-5-7-12)13-8-10-14(22-2)11-9-13/h3-11H,1-2H3,(H,18,21)
54833-61-3Relevant articles and documents
Concerning the reaction mechanism of the hydantoin synthesis according to Biltz, II: Influence of substituents on the direction of the rearrangement
Schwenker,Guo
, p. 45 - 50 (2007/10/02)
From 1-13C-labelled 4-monosubstituted benzils 1a-c and the ureas 3a-d the 5-aryl-5-phenylhydantoines 6a-c and the 3-substituted 5-aryl-5-phenylhydantoines 9a-i were obtaincd as mixtures of isotopomeres. The distribution of 13C-labelling of C-4 and C-5 was determined by mass- and 13C-nmr-spectroscopy. As in the case of benzilic acid rearrangement the a-methylphenyl- and 4-methoxyphenyl-increment, respectively, migrate less easily than does the unsubstituted phenyl group, which in turn migrates less easily than the 4-chlorophenylrest. In the latter case the differences are small and in one example cven slightly reversed. The characteristics of the rearrangement is explained by thermodynamic control of the reaction by preceding equilibria (Schemes 2 and 3).
