17816-50-1

Basic information

• Product Name: 5-(4-methoxyphenyl)-5-phenylimidazolidine-2,4-dione
• Synonyms: 2,4-Imidazolidinedione, 5-(4-methoxyphenyl)-5-phenyl-
• CAS NO: 17816-50-1
• Molecular Formula: C₁₆H₁₄N₂O₃
• Molecular Weight: 282.294
• Mol File: 17816-50-1.mol
• Article Data: 5

Chemical Properties

• Density: 1.256g/cm³
• Refractive Index: 1.594
• CAS DataBase Reference: 5-(4-methoxyphenyl)-5-phenylimidazolidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-methoxyphenyl)-5-phenylimidazolidine-2,4-dione(17816-50-1)
• EPA Substance Registry System: 5-(4-methoxyphenyl)-5-phenylimidazolidine-2,4-dione(17816-50-1)

Safety Data

• Hazardous Substances Data: 17816-50-1(Hazardous Substances Data)

Upstream product

• 100-66-3 methoxybenzene 
• 1023-17-2 4-methoxyphenyl benzyl ketone 
• 1889-77-6 2-bromo-1-(4-methoxy-phenyl)-2-phenyl-ethanone 
• 123-11-5 4-methoxy-benzaldehyde 
• 4254-17-5 4-methoxybenzoin 
• 57-13-6 urea 
• 611-94-9 4-Methoxybenzophenone 
• 151-50-8 potassium cyanide 
• 22711-21-3 4-methoxybenzil 

Downstream Products

• 56079-80-2 3-<3-(4-phenyl-1-piperidyl)propyl>-5-(4-methoxyphenyl)-5-phenylhydantoin hydrochloride 
• 57496-20-5 4'-(S)-hydroxyphenytoin 
• 2784-27-2 5-(4-hydroxyphenyl)-5-phenylhydantoin 
• 54833-61-3 R,S-5-(p-Methoxyphenyl)-3-methyl-5-phenylhydantoin 

Relevant articles and documents

Synthesis of glycoluril catalyzed by potassium hydroxide under ultrasound irradiation

Synthesis of the glycolurils catalyzed by potassium hydroxide was carried out in 17-75% yield at 40 °C in EtOH under ultrasound irradiation. Compared to the method using stirring, the main advantage of the present procedure is milder conditions and shorter reaction time.

One-pot synthesis of phenytoin analogs

A series of phenytoin analogs (5,5-diphenylimidazolidine-2,4-dione or 5,5-diphenyl-hydantoin) were synthesized in 65-75% yield from the corresponding substituted benzils. The same products were also obtained directly from α-hydroxy ketones via one-pot procedure.

5-p-ALKOXYPHENYL-5-BENZYL- AND 5-p-ALKOXYPHENYL-5-PHENYLHYDANTOINS AND THEIR SODIUM SALTS

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