548464-35-3

Basic information

• Product Name: 4-methoxybenzyl (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl ether
• Synonyms: 4-methoxybenzyl (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl ether
• CAS NO: 548464-35-3
• Molecular Weight: 276.419
• Mol File: 548464-35-3.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: 4-methoxybenzyl (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methoxybenzyl (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl ether(548464-35-3)
• EPA Substance Registry System: 4-methoxybenzyl (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl ether(548464-35-3)

Safety Data

• Hazardous Substances Data: 548464-35-3(Hazardous Substances Data)

Upstream product

• 2216-51-5 (-)-menthol 
• 105-13-5 4-Methoxybenzyl alcohol 
• 2746-25-0 p-Methoxybenzyl bromide 
• 866124-70-1 p-methoxybenzyloxydiphenylphosphine 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 775356-24-6 4-(2-isopropyl-5-methyl-cyclohexyloxymethyl)-phenol 
• 824-94-2 p-methoxybenzyl chloride 
• 1450734-54-9 4-methoxybenzyl N-phenyl-2,2,2-trifluoroacetimidate 
• 123-11-5 4-methoxy-benzaldehyde 
• 100867-01-4 (4-methoxybenzyl)(4-nitrophenyl)sulfane 
• 937184-70-8 2-(4-methoxybenzyloxy)-4-methylquinoline 
• 333-27-7 methyl trifluoromethanesulfonate 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 

Downstream Products

• 54879-64-0 N-[(4-methoxyphenyl)methyl]-4-methylbenzenesulfonamide 
• 2216-51-5 (-)-menthol 

Relevant articles and documents

Discriminating non-ylidic carbon-sulfur bond cleavages of sulfonium ylides for alkylation and arylation reactions

A sulfonium ylide participated alkylation and arylation under transition-metal free conditions is described. The disparate reaction pattern allowed the separate activation of non-ylidic S-alkyl and S-aryl bond. Under acidic conditions, sulfonium ylides serve as alkyl cation precursors which facilitate the alkylations. While under alkaline conditions, cleavage of non-ylidic S-aryl bond produces O-arylated compounds efficiently. The robustness of the protocols were established by the excellent compatibility of wide variety of substrates including carbohydrates.

Simple and rapid p-methoxybenzylation of hydroxy and amide groups at room temperature by NaOt-Bu and DMSO

The p-methoxybenzylation of hydroxy and amide groups by p-methoxybenzyl chloride utilizing NaOt-Bu in DMSO is described. p-Methoxybenzylation of sterically hindered menthol using NaOt-Bu in DMSO proceeded faster than the commonly used methods which use Na

Photoredox removal of p-methoxybenzyl ether protecting group with hydrogen peroxide as terminal oxidant

We report a mild protocol for removal of the p-methoxybenzyl ether protecting group under acidic conditions with eosin Y combined with LEDs as a photoredox catalysis system and hydrogen peroxide as the terminal oxidant. This protocol is compatible with ethers derived from primary, secondary, and tertiary alcohols, as well as with various functional groups. The protocol showed unusual selectivity for a tertiary ether over a primary ether. The scale up to gram scale is also explored and identical reactivity is observed.