548483-78-9

Upstream product

• 238758-59-3 (R)-pent-4-ene-1,2-diol 
• 745058-49-5 {(E)-(R)-1-allyl-4-[(4S,6S)-2,2-dimethyl-6-phenethyl-[1,3]dioxan-4-yl]-but-2-enyloxy}-tert-butyldimethylsilane 
• 745058-28-0 {(4S,6S)-4-[2-(tert-butyldimethylsilanyloxy)ethyl]-2,2-dimethyl-6-phenethyl-[1,3]dioxan-(5E)-ylidene}-[(S)-2-methoxymethylpyrrolidin-1-yl]-amine 
• 548483-76-7 (E)-4-((4S,6S)-2,2-Dimethyl-6-phenethyl-[1,3]dioxan-4-yl)-but-2-enal 
• 548483-75-6 (4S,6S)-4-Allyl-2,2-dimethyl-6-phenethyl-[1,3]dioxane 
• 548483-74-5 (3S,5S)-1-phenyl-7-octene-3,5-diol 
• 745058-30-4 (4S,6S)-4-[2-(tert-butyldimethylsilanyloxy)ethyl]-2,2-dimethyl-6-phenethyl-[1,3]dioxan-5-one 
• 745058-45-1 (5R)-2,2,3,3,8,8,9,9-octamethyl-5-(prop-2-en-1-yl)-4,7-dioxa-3,8-disiladecane 
• 745058-38-2 (4R,6S)-4-(2-iodoethyl)-2,2-dimethyl-6-phenethyl-[1,3]dioxane 
• 745058-47-3 (R)-2-(tert-butyldimethylsilanyloxy)-pent-4-en-1-ol 
• 745058-24-6 (R)-2-(tert-butyldimethylsilanyloxy)-pent-4-enal 
• 771476-40-5 2-(N-phenyl-aminooxy)-pent-4-enal 
• 485321-85-5 5-{2-[(4R,6S)-2,2-dimethyl-6-phenethyl-[1,3]dioxan-4-yl]-ethylsulfonyl}-1-phenyl-1H-tetrazole 
• 485321-90-2 5-{2-[(4R,6S)-2,2-dimethyl-6-phenethyl-[1,3]dioxan-4-yl]-ethylsulfanyl}-1-phenyl-1H-tetrazole 

Downstream Products

• 485321-73-1 (R)-6-[(E)-3-((4S,6S)-2,2-Dimethyl-6-phenethyl-[1,3]dioxan-4-yl)-propenyl]-5,6-dihydro-pyran-2-one 

Relevant academic research and scientific papers

Efficient asymmetric syntheses of (+)-strictifolione

The asymmetric synthesis and a formal asymmetric synthesis of (+)-strictifolione are described. As key step in both approaches the Julia-Kocienski olefination to create an E-configured alkene was used. The anti-1,3-diol moiety was synthesized by employing

Total synthesis of (+)-strictifolione.

[reaction: see text] The synthesis of (+)-strictifolione was achieved from 3-phenylproprionaldehyde by using enantioselective allyltitanations to control the stereogenic centers at C6, C4', and C6' and a cross-methathesis to control the configuration of t