54877-02-0Relevant academic research and scientific papers
Efficient Water Reduction with sp3-sp3 Diboron(4) Compounds: Application to Hydrogenations, H–D Exchange Reactions, and Carbonyl Reductions
Flinker, Mathias,Yin, Hongfei,Juhl, René W.,Eikeland, Espen Z.,Overgaard, Jacob,Nielsen, Dennis U.,Skrydstrup, Troels
supporting information, p. 15910 - 15915 (2017/11/23)
A series of crystalline sp3-sp3 diboron(4) compounds were synthesized and shown to promote the facile reduction of water with dihydrogen formation. The application of these diborons as simple and effective dihydrogen and dideuterium sources was demonstrated by conducting a series of selective reductions of alkynes and alkenes, and hydrogen–deuterium exchange reactions using two-chamber reactors. Finally, as the water reduction reaction generates an intermediate borohydride species, a range of aldehydes and ketones were reduced by using water as the hydride source.
BCl3- and TiCl4-mediated reductions of β-hydroxy ketones
Sarko, Christopher R.,Collibee, Scott E.,Knorr, Allison L.,DiMare, Marcello
, p. 868 - 873 (2007/10/03)
Syn-selective reduction protocols for β-hydroxy ketones are described exploiting the intermediacy of titanium and boron chelates derived from TiCl4 and BCl3, respectively. Reductions are conducted at -78°C in CH2Cl2/
Direct enantioselective synthesis of syn-1,3-diols by the reaction of aldehydes with enol silyl ethers in the presence of a chiral borane complex. Successive asymmetric aldol reaction and asymmetric reduction with one promoter
Kaneko, Yuichi,Matsuo, Takao,Kiyooka, Syun-Ichi
, p. 4107 - 4110 (2007/10/02)
A stoichiometric amount of the chiral borane 1 turned out to successively promote the asymmetric aldol reaction of aldehydes with enol silyl ethers and the following asymmetric reduction in one pot to afford syn-1,3-diols with high enantioselectivity.
SILAFUNCTIONAL COMPOUNDS IN ORGANIC SYNTHESIS. 30. INTRAMOLECULAR HYDROSILATION OF ALKENYL ALCOHOLS: A NEW APPROACH TO THE REGIOSELECTIVE SYNTHESIS OF 1,2- AND 1,3-DIOLS
Tamao, Kohei,Tanaka, Tetsu,Nakajima, Takashi,Sumiya, Ritsuo,Arai, Hitoshi,Ito, Yoshihiko
, p. 3377 - 3380 (2007/10/02)
Intramolecular hydrosilation of allyl and homoallyl alcohols and the subsequent oxidative cleavage of the resultant carbon-silicon bond have provided a new approach to the regio-controlled synthesis of 1,2- and/or 1,3-diols.
