549505-65-9 Usage
Uses
Used in Pharmaceutical Industry:
ML 3403 is used as a therapeutic agent for the treatment of diseases involving the p38 MAPK signaling pathway. Its selective inhibition of p38 MAPK makes it an attractive strategy for therapeutic intervention in conditions such as oncogenesis, autoimmune diseases, and inflammatory processes.
Used in Oncology:
ML 3403 is employed as an anticancer agent, targeting the p38 MAPK signaling pathway, which is often dysregulated in various types of cancer. By inhibiting this pathway, ML 3403 can potentially suppress tumor growth and progression, making it a valuable tool in the fight against cancer.
Used in Autoimmune Disease Treatment:
ML 3403 is used as a treatment option for autoimmune diseases, where the p38 MAPK pathway is implicated in the pathogenesis of the condition. Its inhibition can help modulate the immune response and alleviate symptoms associated with autoimmune diseases.
Used in Inflammatory Process Management:
ML 3403 is utilized in the management of inflammatory processes, as the p38 MAPK pathway is involved in the regulation of inflammation. By inhibiting this pathway, ML 3403 can potentially reduce inflammation and provide relief from associated symptoms.
Check Digit Verification of cas no
The CAS Registry Mumber 549505-65-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,4,9,5,0 and 5 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 549505-65:
(8*5)+(7*4)+(6*9)+(5*5)+(4*0)+(3*5)+(2*6)+(1*5)=179
179 % 10 = 9
So 549505-65-9 is a valid CAS Registry Number.
549505-65-9Relevant academic research and scientific papers
Novel substituted pyridinyl imidazoles as potent anticytokine agents with low activity against hepatic cytochrome P450 enzymes
Laufer, Stefan A.,Wagner, Gerd K.,Kotschenreuther, Dunja A.,Albrecht
, p. 3230 - 3244 (2007/10/03)
A series of polysubstituted pyridin-4-yl imidazole inhibitors of p38 MAP (mitogen-activated protein) kinase was prepared as small molecular anticytokine agents and drug candidates for the treatment of chronic inflammatory diseases. The contribution of sub
