Tetrahedron p. 7465 - 7484 (1998)
Update date:2022-08-05
Topics:
Baldwin, Jack E.
Fryer, Andrew M.
Pritchard, Gareth J.
Spyvee, Mark R.
Whitehead, Roger C.
Wood, Mark E.
The syntheses of acromelic acid A 1, allo-acromelic acid A 19 and an approach towards acromelic acid B 2 are described. Palladium (0) catalysed cross-coupling reactions were used to generate C-4 catechol precursors and formation of the pyridone rings was investigated using a biomimetic oxidative cleavage - recyclisation strategy.
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