5524-57-2

Basic information

• Product Name: ETHYL MESITYLGLYOXYLATE
• Synonyms: ETHYL 2-(2,4,6-TRIMETHYLPHENYL)GLYOXYLATE;ETHYL 2-MESITYL-2-OXOACETATE;ETHYL MESITYLGLYOXYLATE;BUTTPARK 153\57-39;Ethyl (2,4,6-trimethylphenyl)glyoxylate~Mesitylglyoxylic acid ethyl ester;Ethylmesitylglyoxylate,97%;ethyl (2,4,6-trimethylphenyl)glyoxylate;mesitylglyoxylic acid ethyl ester
• CAS NO: 5524-57-2
• Molecular Formula: C₁₃H₁₆O₃
• Molecular Weight: 220.26
• Mol File: 5524-57-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 164-165°C 10mm
• Flash Point: 164-165°C/10mm
• Appearance: /
• Density: 1.067g/cm³
• Vapor Pressure: 8.14E-05mmHg at 25°C
• Refractive Index: 1.5120
• BRN: 2970031
• CAS DataBase Reference: ETHYL MESITYLGLYOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL MESITYLGLYOXYLATE(5524-57-2)
• EPA Substance Registry System: ETHYL MESITYLGLYOXYLATE(5524-57-2)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• Safety Statements: 24/25
• Hazardous Substances Data: 5524-57-2(Hazardous Substances Data)

Usage

General Description

Ethyl mesitylglyoxylate is a chemical compound known for its use as a precursor in the synthesis of pharmaceuticals and agrochemicals. It is an ester of mesitylglyoxylate, a molecule consisting of a mesityl group attached to a glyoxylate unit. Ethyl mesitylglyoxylate is a colorless liquid with a variety of applications in the field of organic chemistry, particularly in the development of new drugs and agricultural chemicals. It is also used as a building block for the synthesis of other organic compounds and can be found in academic research laboratories and industrial settings. Due to its potential uses in the production of valuable products, ethyl mesitylglyoxylate is a compound of interest for scientists and researchers seeking to develop new and innovative chemical processes.

InChI:InChI=1/C13H16O3/c1-5-16-13(15)12(14)11-9(3)6-8(2)7-10(11)4/h6-7H,5H2,1-4H3

Upstream product

• 4755-77-5 Ethyl oxalyl chloride 
• 108-67-8 1,3,5-trimethyl-benzene 
• 6957-89-7 Ethyl dichloro-(ethoxy)-acetate 
• 7446-70-0 aluminium trichloride 
• 60-29-7 diethyl ether 
• 95-92-1 oxalic acid diethyl ester 
• 66150-50-3 ethyl 2-hydroxy-2-mesitylacetate 
• 1667-04-5 2-bromomesitylene 
• 57386-83-1 1,3-dichloro-2,4,6-trimethylbenzene 
• 576-83-0 2,4,6-trimethylphenyl bromide 
• 2633-66-1 2-mesitylmagnesium bromide 

Downstream Products

• 4746-81-0 mesitil 
• 3112-46-7 mesitylglyoxylic acid 
• 85905-78-8 Triethylsilanyloxy-(2,4,6-trimethyl-phenyl)-acetic acid ethyl ester 
• 85905-82-4 (Dibutyl-ethyl-silanyloxy)-(2,4,6-trimethyl-phenyl)-acetic acid ethyl ester 
• 85905-86-8 Triisobutylsilanyloxy-(2,4,6-trimethyl-phenyl)-acetic acid ethyl ester 
• 5796-78-1 α-mesityl-2,4,6-trimethylacetophenone 
• 1196988-55-2 C₁₃H₁₈O₃ 
• 1251859-36-5 C₁₆H₂₂O₃ 
• 1402841-31-9 (E)-ethyl 2-mesityl-2-((trimethylsilyl)methylimino)acetate 
• 925-93-9 ethyl [2]alcohol 

Relevant articles and documents

Reactions of organolithiums with dialkyl oxalates. A flow microreactor approach to synthesis of functionalized α-keto esters

Reactions of functionalized aryllithiums with dialkyl oxalates were achieved using a flow microreactor to obtain α-keto esters with high selectivity by virtue of fast 1:1 micromixing.

Simply air: Vanadium-catalyzed oxidative kinetic resolution of methyl o-chloromandelate by ambient air

Vanadium-catalyzed oxidative kinetic resolution (OKR) of methyl o-chloromandelate 2a, key intermediate of the well-known oral antiplatelet agent (S)-clopidogrel, was achieved by ambient air for the first time. The air oxidation system, which was composed of vanadium and tridentate Schiff base ligands derived from amino alcohols and salicylaldehyde derivatives, afforded an efficient and economic approach to the target intermediate with high enantioselectivities (>99% ee).

AMINO SUBSTITUTED PYRIMIDINES AND TRIAZINES

Pyrimidines and triazines of formula (I) wherein R is C 1-6alkyl, amino, mono-or diC 1-6alkylamino; R 1 is hydrogen, C 1-6alkyl, C 3-6alkenyl, hydroxyC 1-6alkyl or C 1-6alkyloxy-C 1-6alkyl; R 2 is C 1-6alkyl, mono-or diC 3-6cycloalkylmethyl, phenylmethyl, substituted phenylmethyl, C 1-6alkyloxy-C 1-6alkyl, hydroxyC 1-6alkyl, C 1-6alkyloxycarbonylC 1-6alkyl, C 3-6alkenyl; or R 1 and R 2 taken together with the nitrogen to which they are attached may form a pyrrolidinyl, morpholinyl or piperidinyl group; X is N or CR 3; R 3 is hydrogen or C 1-6alkyl; R 4 is phenyl or substituted phenyl; A is or--CR 7R 8--wherein R 5 and R 6 each independently are hydrogen or C 1-4alkyl; R 7 is hydrogen or OH, R 8 is hydrogen or C 1-6alkyl; having CRF receptor antagonistic properties; pharmaceutical compositions containing these compounds as active ingredients; methods of treating disorders related to hypersecretion of CRF such as depression, anxiety, substance abuse, by administering an effective amount of a compound of formula (I).