55251-46-2

Basic information

• Product Name: (4-METHOXY-PHENYL)-METHYL-PHENYL-AMINE
• Synonyms: (4-METHOXY-PHENYL)-METHYL-PHENYL-AMINE
• CAS NO: 55251-46-2
• Molecular Formula: C₁₄H₁₅NO
• Molecular Weight: 213.275
• Mol File: 55251-46-2.mol
• Article Data: 93

Chemical Properties

• Boiling Point: 344.9±25.0 °C(Predicted)
• Appearance: /
• Density: 1.077±0.06 g/cm3(Predicted)
• PKA: 1.72±0.32(Predicted)
• CAS DataBase Reference: (4-METHOXY-PHENYL)-METHYL-PHENYL-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-METHOXY-PHENYL)-METHYL-PHENYL-AMINE(55251-46-2)
• EPA Substance Registry System: (4-METHOXY-PHENYL)-METHYL-PHENYL-AMINE(55251-46-2)

Safety Data

• Hazardous Substances Data: 55251-46-2(Hazardous Substances Data)

Usage

General Description

(4-METHOXY-PHENYL)-METHYL-PHENYL-AMINE is a chemical compound with the molecular formula C14H15NO. It is also known by the name 4-methoxy-α-methylbenzylamine and is a member of the amine class of organic compounds. (4-METHOXY-PHENYL)-METHYL-PHENYL-AMINE has a phenyl ring with a methoxy and methyl substituent attached to it. It is commonly used as an intermediate in the synthesis of various pharmaceuticals and organic compounds, and has potential applications in the field of medicinal chemistry. Additionally, it may also have potential uses in the development of new materials and chemical processes.

Upstream product

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• 108-86-1 bromobenzene 
• 623-12-1 4-chloromethoxybenzene 

Downstream Products

• 1359859-46-3 C₂₃H₂₉NO₅ 

Relevant articles and documents

A Simple Synthetic Route to Well-Defined [Pd(NHC)Cl(1-tBu-indenyl)] Pre-catalysts for Cross-Coupling Reactions

The development of robust, more efficient, general, easily accessible Pd(II)–NHC pre-catalysts remains a key issue in cross-coupling applications. A selection of well-defined, air and moisture stable [Pd(NHC)Cl(1-tBu-indenyl)] (NHC=IPr, IPrCl, IMes, SIMes, IPr*) pre-catalysts have been synthesized in good to excellent yields by reacting [Pd(1-tBu-indenyl)(μ-Cl)]2 and various NHC?HCl precursors in the presence of the weak base K2CO3 in green acetone. The synthesized Pd(II)-NHC derivatives displayed excellent catalytic activity in classical Suzuki-Miyaura and Buchwald–Hartwig reactions, especially when IPrCl is employed as ancillary ligand. Additionally, in the challenging Suzuki-Miyaura reaction between esters and arylboronic acids, the [Pd(IPr*)Cl(1-tBu-indenyl)] complex exhibited the optimum catalytic activity under very mild reaction conditions.

Synthesis and catalytic activity of palladium complexes bearingN-heterocyclic carbenes (NHCs) and 1,4,7-triaza-9-phosphatricyclo[5.3.2.1]tridecane (CAP) ligands

The synthesis and characterization of novel palladium complexes bearingN-heterocyclic carbenes (NHCs) and 1,4,7-triaza-9-phosphatricyclo[5.3.2.1]tridecane (CAP) are reported. These organometallic complexes can be easily obtained using two different synthetic strategies that involve either the substitution of the pyridine ligand fromtrans-[Pd(NHC)(Py)Cl2] or by simple addition of the CAP ligand to dimeric species [Pd(NHC)Cl2]2. The mixed NHC/CAP complexes were tested as pre-catalysts in the Buchwald-Hartwig aryl amination coupling, showing good catalytic activity, especially in the case ofcis-[Pd(IPr)(CAP)Cl2].

Pyrazolyl bistriazolyl phosphine compound and application of pyrazolyl bistriazolyl phosphine compound

The invention discloses a pyrazolyl bistriazolyl phosphine compound and application thereof. The invention discloses a compound shown as a formula I. In the formula I, R1 is hydrogen, C1-C6 alkyl or phenyl; R2 and R3 are phenyl; R4 and R5 are independently a C1-C6 alkyl group, a C3-C8 cycloalkyl group, or a phenyl group. The pyrazolyl bistriazolyl phosphine compound disclosed by the invention is stable in property, excellent in catalytic effect and high in selectivity, and can be applied to catalytic coupling of amine, boric acid compounds and halides.