5526-43-2Relevant academic research and scientific papers
REACTIVITY OF 4-HYDROXY-2-PYRONES IN THE DIELS-ALDER REACTIONS
Tanyeli, Cihangir,Tarhan, Okan
, p. 2453 - 2460 (2007/10/02)
Biphenylcarboxylic acid derivatives, and some tetracyclic bridge cycloadducts have been prepared by Diels-Alder reactions of acetylenic and olefinic dienophiles with 4-hydroxy-6-phenyl-2H-pyran-2-one and its methyl ether derivative.
Novel Pyrones from Hypericum mysorense Heyne
Vishwakarma, R. A.,Kapil, R. S.,Popli, S. P.
, p. 466 - 468 (2007/10/02)
The aerial parts of Hypericum mysorense Heyne afford two new pyrones, characterised as 3-(1,1-dimethyl-2-propenyl)-6-phenyl-2,4(3H)-dioxopyran (6) and 3-(1,1-dimethyl-2-propenyl)-2-methoxy-6-phenyl-4H-pyran-4-one (8).The structures have been assigned on t
Use of β-Ketocarboxylic Acids for Syntheses of 6-Substituted 4-Hydroxy-2-pyrones and Acyclic β-Diketones
Ohta, Shunsaku,Tsujimura, Atsuhiko,Okamoto, Masao
, p. 2762 - 2768 (2007/10/02)
β-Ketocarboxylic acids including β-ketoglutaric acid half-esters were cyclized by treating them with 1,1'-carbonyl-diimidazole to give 6-substituted 3-acyl-4-hydroxy-2-pyrones in good yields. 5-Aryl-3,5-dioxo-1-pentanoic acid and monomethyl malonate gave 6-aryl-4-hydroxy-2-pyrone and dimethyl β-ketoglutarate, respectively, on similar treatment.Anibin, one of the Aniba alkaloids, was synthesized from 5-(3-pyridyl)-4-hydroxy-2-pyrone.In addition, it was confirmed that reaction of magnesium β-ketocarboxylate with acylimidazolide gave the corresponding acyclic β-diketone in excellent yield.Keywords - β-ketocarboxilic acid; biogenetic-type synthesis; 4-hydroxy-2-pyrone; β-polyketide; β-ketoglutaric acid; dehydroacetic acid; anibin; Aniba alkaloid; 3-acyl-4-hydroxy-2-pyrone; β-diketone.
