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Tetrahydroxyl diphenylethylene-2-o-glucoside, commonly known as THD-glucoside, is a chemical compound that is widely recognized for its potential skin-lightening properties. It is derived from Vitex agnus-castus, also known as the Chaste Tree, and is valued for its ability to inhibit melanin production by suppressing the activity of tyrosinase, an enzyme involved in melanin synthesis. THD-glucoside is also noted for its oxidative stability and its capacity to be easily absorbed into the skin, making it a favored ingredient in numerous skincare formulations.

55327-45-2

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55327-45-2 Usage

Uses

Used in Skincare Products:
THD-glucoside is utilized as a skin-lightening agent in skincare products for its ability to inhibit melanin production by suppressing the activity of tyrosinase, an enzyme involved in melanin synthesis.
Used in Cosmetics:
In the cosmetics industry, THD-glucoside is employed as a skin-lightening component, leveraging its capacity to reduce melanin production and provide a more even skin tone.
Used in Skincare Formulations:
THD-glucoside is used as an active ingredient in skincare formulations due to its oxidative stability and its ability to be easily absorbed into the skin, contributing to the overall effectiveness of the product. The effectiveness of THD-glucoside can vary based on the concentration used and the overall formulation of the product.

Check Digit Verification of cas no

The CAS Registry Mumber 55327-45-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,3,2 and 7 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 55327-45:
(7*5)+(6*5)+(5*3)+(4*2)+(3*7)+(2*4)+(1*5)=122
122 % 10 = 2
So 55327-45-2 is a valid CAS Registry Number.
InChI:InChI=1/C20H22O9/c21-9-15-16(25)17(26)18(27)20(28-15)29-19-11(7-13(23)8-14(19)24)4-1-10-2-5-12(22)6-3-10/h1-8,15-18,20-27H,9H2/b4-1+/t15-,16-,17-,18-,20+/m1/s1

55327-45-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S,3R,4S,5S,6R)-2-[2,4-dihydroxy-6-[(E)-2-(4-hydroxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol

1.2 Other means of identification

Product number -
Other names (2S,3R,4S,5S,6R)-2-[2,4-dihydroxy-6-[(E)-2-(4-hydroxyphenyl)vinyl]phenoxy]-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:55327-45-2 SDS

55327-45-2Relevant academic research and scientific papers

Water-Assisted/Water-Accelerated Photoreaction of trans-2,3,4′,5-Tetrahydroxystilbene-2- O-β- d -glucoside from the Roots of Polygonum multiflorum

Bao, Ni-Man,Dai, Jin,Liao, Ning-Ling,Ying, Wen-Feng,Zhao, Rong-Hua

, p. 5086 - 5092 (2020)

The photoreaction of 2,3,4′,5-tetrahydroxystilbene-2-O-β-d-glucoside (TSG) has been investigated. Water-assisted/water-accelerated photodimerization of trans-TSG favored the formation of syn-head-to-tail [2 + 2] photocyclobutane under 365 nm irradiation as a result of hydrophobic association and a fluorescent solute-solute aggregate from their excited singlet states. In contrast, irradiation with 254 nm led to [2 + 2] photocycloreversion. The two cyclobutane dimers were first obtained through straightforward photoreaction and identified as multiflorumiside A and multiflorumiside C through the detailed analysis of high-resolution electrospray ionization mass spectrometry and one- and two-dimensional nuclear magnetic resonance. Therefore, trans-TSG should be protected from light and water.

Total Synthesis of Two Glycosylated Stilbenes, Oxyresveratrol 2-O-β- d -Glucopyranoside and 2,3,5,4′-Tetrahydroxystilbene 2-O-β- d -Glucopyranoside

Kumar, Sunil,Lee, Hsueh-Yun,Liou, Jing-Ping

, p. 1294 - 1301 (2017/05/31)

Glycosylated stilbenes are biologically active secondary metabolites of plants and have the potential to alleviate a broad range of human diseases. However, some of these compounds are not naturally abundant, and thus the synthesis of such molecules is de

Isomeric effect on H/D exchange of resveratrol studied by NMR spectroscopy

Jiang, Haipeng,Fang, Hanjun,Jiang, Ling,Zheng, Limin,Wang, Nian,Zheng, Anmin,Deng, Feng,Liu, Maili

experimental part, p. 2281 - 2286 (2011/10/12)

Resveratrol (3,5,4′-trihydroxylstilbene), a phytoalexin in response to injury or fungal attack, is found in grapes and other food products. It has been well documented that the compound has beneficial effects as hypolipidemic, anticancer, antiviral, neuro

USE OF HYDROXYSTILBENES FOR DYEING, READY-TO-USE COMPOSITION CONTAINING THEM AND DYEING PROCESS

-

, (2008/06/13)

The invention relates to the use of hydroxystilbenes for dyeing, to ready-to-use dye compositions comprising them, to a dyeing process using them and to a multi-compartment device containing the compositions used in the processes of the invention.

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