85565-92-0

Upstream product

• 85565-94-2 2-bromo-3,5-bis(benzyloxy)benzaldehyde 
• 99-10-5 3,5-Dihydroxybenzoic acid 
• 24131-31-5 3,5-dibenzyloxybenzyl alcohol 
• 100-44-7 benzyl chloride 
• 13246-46-3 2,4-dibenzyloxybenzaldehyde 
• 6195-80-8 2,4-bis(benzyloxy)phenol 
• 100-97-0 hexamethylenetetramine 
• 100-39-0 benzyl bromide 
• 95-01-2 2,4-Dihydroxybenzaldehyde 

Downstream Products

• 55327-45-2 2,4-dihydroxy-6-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl-β-D-glucopyranoside 

Relevant academic research and scientific papers

Total Synthesis of Two Glycosylated Stilbenes, Oxyresveratrol 2-O-β- d -Glucopyranoside and 2,3,5,4′-Tetrahydroxystilbene 2-O-β- d -Glucopyranoside

Glycosylated stilbenes are biologically active secondary metabolites of plants and have the potential to alleviate a broad range of human diseases. However, some of these compounds are not naturally abundant, and thus the synthesis of such molecules is de

Aromatic Hydroxylation. Hydroxybenzaldehydes from Bromobenzaldehydes via Reaction of in Situ Generated, Lithiated α-Morpholinobenzyl Alkoxides with Nitrobenzene

A general method for the one-step conversion of bromobenzaldehydes to the corresponding hydroxybenzaldehydes has been developed.The method involves in situ protection of the aldehyde function of the bromobenzaldehyde as its lithium morpholinoalkoxide, followed by lithium-bromine exchange, reaction with nitrobenzene at -75 deg C, and a subsequent acidic workup.The method has been applied to the synthesis of 4,5-dimethoxy-3-hydroxy- (1a), 3,5-dimethoxy-2-hydroxy- (2a), 3,5-bis(benzyloxy)-2-hydroxy- (2b), 3,4-dimethoxy-2-hydroxy- (14), 3-hydroxy-4,5-(methylenedioxy)- (16), and 4,5-dimethoxy-2-hydroxybenzaldehydes (18) from the bromobenzaldehydes 4, 12a, 12b, 13, 15, and 17, respectively.