55368-83-7Relevant articles and documents
Microwave-assisted synthesis of new 2-aryl and 2-alkylimidazolones and evaluation of their in vitro anticancer activity and their in vivo toxicity on zebrafish embryos
Bou Zeid, Samar,Hamade, Aline,Najjar, Fadia,Carreaux, Francois,Eid, Samar
, p. 2549 - 2560 (2021/02/05)
Herein we describe the synthesis of five new 2-aryl and 2-alkylimidazolone derivatives via an effective one-pot synthetic strategy assisted by microwave irradiations which allowed us to access the desired product in a reduced time reaction compared to the
Synthesis method of 1-alkyl-3, 5-aryl substituted 1, 2, 4 triazole compound
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Paragraph 0071; 0074-0076; 0101; 0104-0106, (2021/03/13)
The invention discloses a preparation method of a 1-alkyl-3, 5-aryl substituted 1, 2, 4 triazole compound, which comprises the following steps: reacting a cyano group-containing compound 1 with acetylchloride at 10-40 DEG C to convert the cyano group into an imino group, thereby generating a compound 2; carrying out amidation reaction on the compound 2 and a formyl chloride group-containing compound 3 at the temperature of 0 DEG C to 60 DEG C to generate a compound 4; subjecting the compound 4 and an alkyl hydrazine compound 5 to an oxidation ring closing reaction at the temperature of 0 DEGC to 60 DEG C, and generating a 1-alkyl-3, 5-aryl substituted 1, 2, 4-triazole compound 6; and carrying out hydrolysis reaction on ester in the compound 6 at the temperature of 25 DEG C to 80 DEG C togenerate carboxyl, so as to obtain the 1-alkyl-3, 5-aryl substituted 1, 2, 4 triazole compound 7 with halogen and carboxyl on two different aromatic rings respectively. The method has the advantagesof wide raw material application range, mild conditions, good reaction selectivity, no introduction of metal residues, easiness in operation and the like.
Fluorescent organic light emitting elements having high efficiency
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Page/Page column 90, (2019/07/12)
An organic light-emitting element which emits delayed fluorescence comprising specifically substituted 1,2,4-triazole derivatives, 1,2,4-oxadiazole derivatives or 1,2,4-thiadiazole derivatives in the light-emitting layer, a light-emitting layer comprising