55379-71-0

Usage

Uses

Used in Pharmaceutical Industry:
PYRROLIDINE-1-CARBOXYLIC ACID PHENYL ESTER is used as a building block for the synthesis of various pharmaceuticals. Its unique structure allows it to be incorporated into the development of new drugs, contributing to the advancement of medicine.
Used in Organic Synthesis:
In the field of organic synthesis, PYRROLIDINE-1-CARBOXYLIC ACID PHENYL ESTER serves as a reagent, facilitating the creation of a wide range of organic compounds. Its versatility in reactions makes it an essential component in the synthesis process.
Used as a Precursor for Agrochemicals:
PYRROLIDINE-1-CARBOXYLIC ACID PHENYL ESTER is utilized as a precursor in the synthesis of agrochemicals, playing a crucial role in the development of pesticides and other agricultural products that contribute to increased crop yields and protection against pests.
Used in Flavor and Fragrance Industry:
This chemical compound is also employed in the production of flavors and fragrances, adding to the diverse applications of PYRROLIDINE-1-CARBOXYLIC ACID PHENYL ESTER. Its ability to contribute to the creation of various scents and tastes makes it a valuable asset in this industry.

InChI:InChI=1/C11H13NO2/c13-11(12-8-4-5-9-12)14-10-6-2-1-3-7-10/h1-3,6-7H,4-5,8-9H2

Upstream product

• 1885-14-9 phenyl chloroformate 
• 681439-88-3 1-(2-methoxy-benzenesulfonyl)-pyrrolidine 
• 100-66-3 methoxybenzene 
• 108-95-2 phenol 
• 1192-63-8 1-pyrrolidinecarbonyl chloride 
• 34085-53-5 phenyl bis(2-hydroxyethyl)carbamate 
• 10130-87-7 o-Methoxybenzenesulfonyl chloride 
• 123-75-1 pyrrolidine 

Downstream Products

• 1092074-43-5 3-(N-(phenoxycarbonyl)formamido)propanoic acid 
• 121751-70-0 1-phenoxycarbonyl-2-oxopyrrolidine 
• 98841-68-0 (2-hydroxy-phenyl)(pyrrolidin-1-yl)methanone 
• 1414838-08-6 (E)-2-(3-ethoxy-3-oxoprop-1-en-1-yl)phenyl pyrrolidine-1-carboxylate 
• 69001-14-5 2-methoxy-pyrrolidine-1-carboxylic acid phenyl ester 

Relevant academic research and scientific papers

Nickel-catalyzed reductive cyclization of alkyl dihalides

The reductive coupling protocol to intramolecular cyclization of dihaloalkanes is presented. It leads to five- and six-membered rings, with the former being more efficient. The incorporation of secondary alkyl halides generally promotes coupling efficiency. To the best of our knowledge, this is the first catalytic ring-closure reaction arising from dihaloalkanes under chemical reductive conditions.

Anionic ortho-fries rearrangement, a facile route to arenol-based mannich bases

Phenol and 1-naphthol-based carbamates undergo the anionic ortho-Fries rearrangement to their corresponding amides. Bulky substitution at position 8 of 1-naphthol-based carbamates makes the rearrangement an exclusive reaction, even at -90 C, under a variety of conditions. The amides can be efficiently reduced to the corresponding Mannich bases. A novel route to 7-[(dialkylamino)methyl]-8- hydroxy-1-naphthaldehydes is presented.

Achieving functional group diversity in parallel synthesis: solution-phase synthesis of a library of ureas, carbamates, thiocarbamates, and amides using carbamoylimidazolium salts

A convenient protocol for the parallel solution-phase synthesis of a library of thiocarbamates, ureas, carbamates, and amides from carbamoylimidazolium salts has been developed. The crystalline carbamoylimidazolium salts are readily synthesized from secon

A simple method for the preparation of di-, tri- and tetrasubstituted non-symmetrical ureas

The synthesis of a series of di-, tri- and tetrasubstituted non-symmetrical ureas is described. Di- and trisubstituted ureas are prepared in excellent yield by treatment of a phenyl carbamate in a self-tunable single-mode microwave synthesizer with a primary or secondary amine. The synthetically more challenging tetrasubstituted urea can be prepared using the 4-nitrophenyl carbamate and a secondary amine. Georg Thieme Verlag Stuttgart.

AZAARENE DERIVATIVES

A compound represented by the general formula: wherein X1 represents a nitrogen atom or a group represented by the formula -CR10=; X2 represents a nitrogen atom or a group represented by the formula -CR11=; Y represents an oxygen atom or the like; R1 represents a C1-6 alkoxy group, an optionally substituted C6-10 aryloxy group, a group represented by the formula -NR12aR12b or the like; R2 represents a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like; R3, R4, R5, R6, R7, R8, R10 and R11 each independently represent a hydrogen atom, a halogen atom, an optionally substituted C1-6 alkyl group, or the like; R9 represents a group represented by the formula -NR16aR16b or the like; and R12a, R12b, R16a and R16b each independently represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, a salt thereof, or a hydrate of the foregoing.

ortho-anisylsulfonyl as a protecting group for secondary amines: Mild Ni0-catalyzed hydrodesulfonylation

A potentially good alternative to the tosyl group (Ts) as a protecting group for amines is N-ortho-anisylsulfonyl (Ans), which is readily cleaved under mild, Ni0-catalyzed reductive conditions (see scheme, acac = acetylacetonate). N-Anisylation of primary amines followed by alkylation and deprotection provides a route to a range of secondary amines.

α-Haloalkyl Haloformates and Related Compounds 1. A Convenient Synthesis of Carbamates via Chloromethyl Carbamates

The preparation of carbamates under mild conditions utilizing a new class of activated carbonates (containing chloromethyl function) is described.