55546-61-7Relevant academic research and scientific papers
Sulfonium Ylides by (3+2) Cycloaddition of Arynes with Vinyl Sulfides: Stereoselective Synthesis of Highly Substituted Alkenes
Li, Yuanming,Mück-Lichtenfeld, Christian,Studer, Armido
supporting information, p. 14435 - 14438 (2016/11/11)
The reaction of in situ generated arynes with vinyl sulfides provides benzannulated sulfonium ylides in a (3+2) cycloaddition. Trapping of the intermediate ylides with electrophiles (proton transfer or a second aryne addition) and subsequent β-elimination give rise to di-, tri-, or tetrasubstituted alkenes with high stereoselectivity. Experimental studies and DFT calculations provide insight into the mechanisms of these cascade reactions.
Synthesis and evaluation of substrate analogues as mechanism-based inhibitors of type II isopentenyl diphosphate isomerase
Walker, Joel R.,Rothman, Steven C.,Poulter, C. Dale
, p. 726 - 729 (2008/09/17)
(Chemical Equation Presented) Type 2 isopentenyl diphosphate isomerase (IDI-2), which catalyzes the interconversion of isopentenyl diphosphate and dimethylallyl diphosphate, contains a tightly bound molecule of FMN. To probe the mechanism of the reaction,
Chemoselective deoxygenation of sulfoxides with titanium tetraiodide
Shimizu,Shibuya,Hayakawa
, p. 1437 - 1438 (2007/10/03)
Chemoselective deoxygenation of sulfoxides was carried out using TiI4 as a reducing agent to give sulfides in good to excellent yields.
Experimental and Theoretical Study of the Radical-Chain Addition of Benzenethiol to Heterosubstituted Allenes
Pasto, Daniel J.,L'Hermine, Gael
, p. 685 - 694 (2007/10/02)
The radical-chain addition of benzenethiol to phenylallene (PHA), methoxyallene (MEOA), carbomethoxyallene (CBA), cyanoallene (CNA), chloroallene (ClA), and (phenylthio)- and allene (PHSA and MPHSA) has been studied.In all cases, exc
