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5556-23-0

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5556-23-0 Usage

Description

3-Hydroxy-5-phenyl-2-thiophenecarboxylic acid methyl ester, also known as mocetinostat, is a synthetic hydroxamic acid derivative of thiophene carboxylic acid with potential pharmaceutical applications. As a histone deacetylase inhibitor, it can block enzymes that remove acetyl groups from histone proteins, potentially leading to changes in gene expression.

Uses

Used in Oncology:
3-Hydroxy-5-phenyl-2-thiophenecarboxylic acid methyl ester is used as an anticancer agent for the treatment of various cancers. It has shown promise in preclinical and clinical trials, modulating gene expression and exhibiting potential efficacy against different types of cancer.
Used in Neurodegenerative Disorders:
3-Hydroxy-5-phenyl-2-thiophenecarboxylic acid methyl ester is used as a potential therapeutic agent for neurodegenerative disorders. Its ability to modulate gene expression may contribute to the development of treatments for such conditions.
Used in HIV Treatment:
3-Hydroxy-5-phenyl-2-thiophenecarboxylic acid methyl ester is used as a potential treatment for HIV due to its ability to reactivate latent virus in infected cells, offering a novel approach to target and eliminate the virus.
Overall, 3-Hydroxy-5-phenyl-2-thiophenecarboxylic acid methyl ester is a compound with diverse potential applications in the field of medicine and pharmaceuticals, particularly in oncology, neurodegenerative disorders, and HIV treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 5556-23-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,5,5 and 6 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 5556-23:
(6*5)+(5*5)+(4*5)+(3*6)+(2*2)+(1*3)=100
100 % 10 = 0
So 5556-23-0 is a valid CAS Registry Number.

5556-23-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-Hydroxy-5-phenyl-thiophen-2-carbonsaeure-methylester

1.2 Other means of identification

Product number -
Other names methyl 3-hydroxy-5-phenylthiophene-2-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5556-23-0 SDS

5556-23-0Relevant articles and documents

Bromoarylation of Methyl 2-Chloroacrylate under Meerwein Conditions for the Synthesis of Substituted 3-Hydroxythiophenes

Ostapiuk, Yurii V.,Shehedyn, Maksym,Barabash, Oksana V.,Demydchuk, Bohdan,Batsyts, Sviatoslav,Herzberger, Colin,Schmidt, Andreas

, p. 732 - 740 (2021/11/20)

Methyl 3-aryl-2-bromo-2-chloropropanoates can be prepared by Meerwein reaction from methyl 2-chloroacrylate and various arenediazonium salts under copper(II) bromide catalysis. The resulting readily available compounds were used as starting materials in reactions with substituted methanethiols for the construction of substituted 3-hydroxythiophenes which have not yet been accessible by other routes. Structural variety of the obtained 2-substituted 5-aryl-3-hydroxythiophenes has been achieved due to a wide range of available starting materials, including both anilines and thiols.

N-1H-Tetrazol-5-yl-(5-Ring)-carboxamide-derivatives, a process for their manufacture, and the use thereof

-

, (2008/06/13)

-

N-1H-tetrazol-5-yl-2-thiophene carboxamides, N-1H-tetrazol-5-yl-2-pyrrole carboxamides, N-1H-tetrazol-5-yl-2-furan carboxamides, and anti-allergic and anti-inflammatory use thereof

-

, (2008/06/13)

The present invention is for compounds having the formula of N-1H-tetrazol-5-yl-2-thiophenecarboxamides, N-1H-tetrazol-5-yl-2-pyrrolecarboxamides, N-1H-tetrazol-5-yl-2-furancarboxamides or analogs of each of the carboxamides. The compounds are useful for the treatment of allergic or inflammatory conditions or diseases. Thus, pharmaceutical compositions and methods of use are also the invention. Processes of preparation for the compounds are also the invention.

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