5556-54-7Relevant academic research and scientific papers
Plasma-Polymerized Phlorotannins and Their Enhanced Biological Activities
Baek, Ki Ho,Jo, Cheorun,Kim, Hyun-Joo,Kim, Tae Hoon,Lee, Byong Won,Park, Sanghoo,Yong, Hae In
, p. 2357 - 2365 (2020)
Here, we investigated the effect of cold plasma (CP) on the biological activities of phloroglucinol. Phloroglucinol (7.92 and 15.84 mM in methanol) was treated with air dielectric barrier discharge plasma at 250 W. In vitro, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activity and ferrous-reducing antioxidant power (FRAP) values of phloroglucinol increased in plasma treatment in a time-dependent manner. CP treatment of phloroglucinol decreased the lipid oxidation of oil emulsion during storage and increased the antimicrobial activity against Bacillus cereus, Escherichia coli O157:H7, and Staphylococcus aureus. Angiotensin-converting enzyme (ACE) inhibitory activity of phloroglucinol increased and total phenolic content decreased based on CP treatment. The CP-induced polymerization of phloroglocinol to phlorotannin derivatives was identified using high-performance liquid chromatography with UV detector and electrospray ionization/mass spectrometry (HPLC-UV-ESI/MS) method. Consequently, the polymer structure of phloroglucinol was found in the CP-treated phloroglucinol. In addition, CP enhances the biological activity of phloroglucinol and could be applied to bioactive materials in food and related industries.
Hydrogenation of substituted aromatic aldehydes: Nucleophilic trapping of the reaction intermediate, application to the efficient synthesis of methylene linked flavanol dimers
Boyer, Fran?ois-Didier,Ducrot, Paul-Henri
, p. 5177 - 5180 (2007/10/03)
The synthesis of dimeric flavanols is the consequence of the possible trapping of the reaction intermediates generated in the course of the reductive hydrogenation of substituted benzaldehydes. The scope of this reaction is investigated.
