55626-14-7Relevant academic research and scientific papers
Efficient synthesis of 1,5-benzodiazepine derivatives by ytterbium trichloride-catalyzed condensation of o-phenylenediamine and ketones
Wu, Jianting,Xu, Fan,Zhou, Zhuqing,Shen, Qi
, p. 457 - 464 (2006)
1,5-Benzodiazepines are synthesized in good to excellent yields by ytterbium trichloride (YbCl3)-catalyzed condensation of o-phenylenediamine and ketones under mild and solvent-free conditions. The Lewis acid-type catalyst, ytterbium trichlorid
Indium(III) bromide: A novel and efficient reagent for the rapid synthesis of 1,5-benzodiazepines under solvent-free conditions
Yadav,Reddy,Praveenkumar,Nagaiah
, p. 480 - 484 (2005)
o-Phenylenediamines (OPDA) undergo rapid condensation with ketones having hydrogens at the α-position in the presence of 10 mol% indium(III) bromide under extremely mild reaction conditions to afford the corresponding 1,5-benzodiazepines in excellent yiel
An efficient synthesis of 1,5-benzodiazepine derivatives catalyzed by a solid superacid sulfated zirconia
Reddy, Benjaram M.,Sreekanth, Pavani M.
, p. 4447 - 4449 (2003)
2,3-Dihydro-1H-1,5-benzodiazepines are synthesized by the condensation of o-phenylendiamine and various ketones in the presence of a versatile solid superacid catalyst 'sulfated zirconia' under solvent free conditions.
Montmorillonite K10: An efficient catalyst for solvent-free synthesis of 1,5-benzodiazepine derivatives
An, Li-Tao,Ding, Fei-Qing,Zou, Jian-Ping,Lu, Xiao-Hua
, p. 1259 - 1267 (2008)
2,3-Dihydro-1H-1,5-benzodiazepines have been synthesized under solvent-free conditions in good yields from o-phenylenediamine and ketones catalyzed by montmorillonite K10. This method has advantages of mild reaction conditions, simple operation, and envir
Perchloric acid supported on silica catalyzed efficient synthesis of 1,5-benzodiazepines
Meshram,Reddy,Murthy, P. Vishnu,Yadav
, p. 4117 - 4122 (2007)
Perchloric acid adsorbed on silica gel efficiently catalyzed the condensation of o-phenylenediamines (OPDA) with cyclic and acyclic ketones at ambient temperature to afford 1,5-benzodiazepines in good yields under solvent-free conditions. Copyright Taylor
Au(I)eN-heterocyclic carbene complex-catalyzed synthesis of 1-substituted benzo[b][1,4]diazepines from N-substituted o-phenylenediamines and terminal alkynes
Guo, Pei,Zeng, Xiaoming,Chen, Si,Luo, Meiming
, p. 438 - 442 (2014)
1-Substituted benzo[b][1,4]diazepines which are difficult to synthesize by traditional methods have been prepared by an Au(I)-N-heterocyclic carbene complex-catalyzed tandem hydroamination/cyclization process. This protocol features the one-pot formation
Ceric ammonium nitrate (CAN) promoted efficient synthesis of 1,5-benzodiazepine derivatives
Varala, Ravi,Enugala, Ramu,Nuvula, Sreelatha,Adapa, Srinivas R.
, p. 1009 - 1014 (2006)
Ceric ammonium nitrate was found to be an efficient reagent for the preparation of 1,5-benzodiazepine derivatives of a wide range of substituted o-phenylenediamines and electronically divergent ketones in moderate to excellent isolated yields (60-98%) und
Molecular iodine catalyzed highly rapid synthesis of 1,5-benzodiazepine derivatives under mild conditions
Bandgar,Bettigeri, Sampada V.,Joshi, Neeta S.
, p. 1447 - 1453 (2004)
Rapid reaction of o-phenylenediamines with both cyclic and acyclic ketones in the presence of catalytic amount of iodine afforded 1,5-benzodiazepine derivatives in excellent yields at room temperature.
A new, efficient and environmentally benign protocol for the synthesis of 1,5-benzodiazepines using cerium(III) chloride/sodium iodide supported on silica gel
Sabitha, Gowravaram,Kiran Kumar Reddy,Bhaskar Reddy,Mallikarjuna Reddy,Yadav
, p. 921 - 923 (2004)
A novel and green approach has been described for the synthesis of 2,3-dihydro-1H-1,5-benzodiazepines from o-phenylenediamines and ketones using cerium(III) chloride/sodium iodide supported on silica gel under mild and heterogeneous conditions. The reacti
Synthesis of 1,5-Benzodiazepine derivatives catalysed by zinc chloride
Pasha, Mohamed Afzal,Jayashankara, Vaderapura Puttaramegowda
, p. 1017 - 1023 (2006)
2,3-Dihydro-1H-1,5-benzodiazepines have been synthesized by the condensation of o-phenylenediamine (OPDA) with cyclic or acyclic ketones in the presence of zinc chloride as catalyst at 80-85 °C. The yields are high and the reactions go to completion withi
