55705-16-3Relevant academic research and scientific papers
1,2-Dibromoethane and KI mediated α-acyloxylation of ketones with carboxylic acids
Wang, Xujie,Li, Gangsheng,Yang, Yanan,Jiang, Jianshuang,Feng, Ziming,Zhang, Peicheng
supporting information, p. 711 - 714 (2019/09/30)
The 1,2-dibromoethane- and KI-mediated α-acyloxylation of ketones is reported in moderate to good yield without the use of transition metals and strong oxidants. Various acids are well tolerated with wide functional group compatibility. An 1,2-dibromoethane- and KI-catalysed reaction mechanism is proposed based on the results of control experiments.
Copper-catalyzed α-C-H acyloxylation of carbonyl compounds with terminal alkynes
Li, Jiao,Yang, Zan,Yang, Tao,Yi, Jianmin,Zhou, Congshan
supporting information, p. 1581 - 1584 (2018/02/09)
Herein, a copper/TBHP catalyst system for the α-C-H acyloxylation of carbonyl compounds is developed using terminal alkynes as the acyloxy source. A variety of carbonyl compounds and terminal alkynes are tolerated in this reaction. In addition, its possible mechanism is proposed.
Metal-free one-pot α-benzoxylation of benzylic alcohols with acids or aldehydes
Zhu, Yefu,Zheng, Yong,Song, Weibin,Wei, Bole,Xuan, Lijiang
supporting information, p. 368 - 371 (2018/01/04)
A metal-free strategy has been developed for α-benzoxylation of benzylic alcohols with acids or aldehydes. The reaction proceeds via sequential oxidation and α-benzoxylation in one pot. Importantly, the reactions are performed in metal-free condition and utilize cheap aqueous TBHP as an oxidant, affording α-benzoxy ketones in moderate to good yields.
I2/TBHP-mediated oxidative coupling of ketones and toluene derivatives: a facile method for the preparation of α-benzoyloxy ketones
Chen, Cui,Liu, Weibing,Zhou, Peng,Liu, Hailing
, p. 20394 - 20397 (2017/04/19)
An efficient oxidative approach was developed for the α-benzoyloxylation of ketones using tert-butyl hydroperoxide (TBHP). This process provided facile access to a wide range of α-benzoyloxy ketones in good to excellent yields via the direct oxidative α-benzoyloxylation of a structurally diverse series of ketones using simple arylmethane compounds.
Bu4NI-Catalyzed α-Oxyacylation of Carbonyl Compounds with Toluene Derivatives
Li, Chengliang,Jin, Tao,Zhang, Xinglu,Li, Chunju,Jia, Xueshun,Li, Jian
supporting information, p. 1916 - 1919 (2016/05/19)
A TBAI (tetrabutylammonium iodide)-catalyzed direct α-oxyacylation of carbonyl compounds from readily available toluene derivatives has been developed. The distinguished features of this metal-free protocol include the employment of simple starting material, a wide carbonyl compound scope, and mild reaction conditions.
NBu4NI-catalyzed α-benzoxylation of ketones with terminal aryl alkenes
Mondal, Buddhadeb,Sahoo, Subas Chandra,Pan, Subhas Chandra
, p. 3135 - 3140 (2015/05/13)
A metal-free protocol for the α-benzoxylation of ketones has been developed by using terminal aryl alkenes as an arylcarboxy surrogate. Moderate to good yields were attained for a variety of propiophenones and acetophenones by using tetra-n-butylammonium iodide (TBAI) as the catalyst and tert-butyl hydroperoxide (TBHP) as the oxidant under ambient reaction conditions. An efficient synthesis for the α-benzoxylation of aryl ketones has been developed by using terminal aryl alkenes as the arylcarboxy surrogate. The products were obtained in moderate to good yields for a broad scope of substrates. Tetra-n-butylammonium iodide (TBAI) and tert-butyl hydroperoxide (TBHP) were employed as the catalyst and oxidant, respectively.
METHOD FOR PRODUCING ALPHA-ACYLOXYCARBONYL COMPOUND AND NOVEL ALPHA-ACYLOXYCARBONYL COMPOUND
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Page/Page column 7; 9, (2013/02/27)
A method for producing an α-acyloxycarbonyl compound of the present invention includes performing an intermolecular reaction between a carboxylic acid and a carbonyl compound selected from the group consisting of ketones, aldehydes, and esters, which have
In situ generated (Hypo)iodite catalysts for the direct α-oxyacylation of carbonyl compounds with carboxylic acids
Uyanik, Muhammet,Suzuki, Daisuke,Yasui, Takeshi,Ishihara, Kazuaki
supporting information; experimental part, p. 5331 - 5334 (2011/07/08)
It′s the iodine: The intra- and intermolecular title reaction is catalyzed by an in situ generated ammonium (hypo)iodite species. Either H 2O2 or tert-butyl hydroperoxide (TBHP) can be used as an environmentally benign oxidant and a wide range of substrates react to give the corresponding α-acyloxycarbonyl compounds in good to excellent yields.
