557056-07-2

Basic information

• Product Name: 4-Cbz-1-Boc 2-(hydroxyMethyl)piperazine
• Synonyms: 4-Cbz-1-Boc 2-(hydroxyMethyl)piperazine;4-benzyl 1-tert-butyl 2-(hydroxymethyl)piperazine-1,4-dicarboxylate
• CAS NO: 557056-07-2
• Molecular Formula: C18H26N2O5
• Molecular Weight: 350.40944
• Mol File: 557056-07-2.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 480.5±30.0 °C(Predicted)
• Appearance: /
• Density: 1 +-.0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 14.97±0.10(Predicted)
• CAS DataBase Reference: 4-Cbz-1-Boc 2-(hydroxyMethyl)piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Cbz-1-Boc 2-(hydroxyMethyl)piperazine(557056-07-2)
• EPA Substance Registry System: 4-Cbz-1-Boc 2-(hydroxyMethyl)piperazine(557056-07-2)

Safety Data

• Hazardous Substances Data: 557056-07-2(Hazardous Substances Data)

Usage

General Description

4-Cbz-1-Boc 2-(hydroxyMethyl)piperazine is a chemical compound with the molecular formula C19H28N2O4. It is an important intermediate in the synthesis of pharmaceutical compounds and is commonly used in organic chemistry reactions. The compound is a derivative of piperazine and contains both a carbobenzyloxy (Cbz) and tert-butoxycarbonyl (Boc) protecting groups, which are commonly used in organic synthesis to protect functional groups. 4-Cbz-1-Boc 2-(hydroxyMethyl)piperazine is used as a building block in the synthesis of various pharmaceutical drugs and has a wide range of applications in medicinal chemistry and drug development.

Upstream product

• 138775-02-7 (2R)-4-[(benzyloxy)carbonyl]-1-[(tert-butoxy)carbonyl]piperazine-2-carboxylic acid 
• 1313278-42-0 (S)-4-benzyl 1-tert-butyl 2-methyl piperazine-1,2,4-tricarboxylate 
• 138775-03-8 (S)-4-(benzyloxycarbonyl)-1-(tert-butyloxycarbonyl)-piperazine-2-carboxylic acid 
• 138812-69-8 (S)-4-(benzyloxycarbonyl)piperazine-2-carboxylic acid 
• 501-53-1 benzyl chloroformate 
• 147650-70-2 (2S)-piperazine-2-carboxylic acid 
• 930837-02-8 benzyl (3S)-3-(hydroxymethyl)piperazine-1-carboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 313706-16-0 (2S)-2-ethoxycarbonylpiperazine-1,4-dicarboxylic acid 4-benzyl ester 1-tert-butyl ester 
• 129799-15-1 piperazine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 
• 1214196-85-6 1-(tert-butoxycarbonyl)piperazine-2-carboxylic acid 
• 129799-14-0 4-benzyl 1-(tert-butyl) 2-methyl piperazine-1,2,4-tricarboxylate 

Downstream Products

• 1030377-21-9 (S)-2-(hydroxymethyl)piperazine-1-carboxylic acid tert-butyl ester 
• 169448-87-7 (R)-2-(hydroxymethyl)piperazine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

Novel aminopyrimidine EGFR inhibitor

The present invention provides a novel aminopyrimidine compound that is a selective inhibitor of the fourth generation EGFR (T790M/C797S mutation), a pharmaceutical composition containing the compound, a useful intermediate for preparing the compound, and

ROR [gamma]t inhibitor, preparation method and application thereof

The invention relates to the technical field of medicines, in particular to an ROR [gamma]t inhibitor, a preparation method and application thereof. The invention also relates to a pharmaceutical composition containing the compound, a method for preparing the pharmaceutical composition, and application of the compound or the pharmaceutical composition in treatment or prevention of ROR [gamma]t-mediated cancers, inflammations or autoimmune diseases of mammals, especially human beings.

Pan-Tropic Entry Inhibitors

This disclsore relates to compounds according to Formula (I), salts, prodrugs and pharmaceutical formulation comprising the compound are provided herein for the treatment of CXCR4 and CCR5 related conditions. The conditions may include viral infections, a