55760-16-2

Basic information

• Product Name: 1-Methyl-2-(1-methylvinyl)cyclobutaneacetic acid
• Synonyms: 1-Methyl-2-(1-methylvinyl)cyclobutaneacetic acid
• CAS NO: 55760-16-2
• Molecular Formula: C₁₀H₁₆O₂
• Molecular Weight: 0
• Mol File: 55760-16-2.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Methyl-2-(1-methylvinyl)cyclobutaneacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyl-2-(1-methylvinyl)cyclobutaneacetic acid(55760-16-2)
• EPA Substance Registry System: 1-Methyl-2-(1-methylvinyl)cyclobutaneacetic acid(55760-16-2)

Safety Data

• Hazardous Substances Data: 55760-16-2(Hazardous Substances Data)

Upstream product

• 412011-51-9 2-acetyl-1-methyl-1-cyclobutaneacetic acid 
• 2065-66-9 methyl-triphenylphosphonium iodide 
• 53171-63-4 (+/-)-3-oximino-1,4,4-trimethylbicyclo<3.2.0>heptane 
• 53171-52-1 1,4,4-trimethyl-cis-bicyclo<3.2.0>heptan-2-one 
• 503-93-5 eucarvone 
• 13404-66-5 6-methylbicyclo<4.2.0>octan-2-one 
• 28117-16-0 cis-6-methylbicyclo<4.2.0>oct-3-en-2-one 
• 73416-58-7 cis-(+/-)2,5-dimethylbicyclo<3.2.0>heptan-2-ol 
• 50459-35-3 (+/-)5-methylbicyclo<3.2.0>heptan-2-one 
• 116382-26-4 (+/-)2,5-dimethylhepta-1,6-dien-5-ol 
• 20962-70-3 ethyl 2-acetyl-4-methylpent-4-enoate 
• 3240-09-3 5-methyl-5-hexen-2-one 
• 19493-09-5 Methylenetriphenylphosphorane 
• 74-95-3 1,1-dibromomethane 

Downstream Products

• 26532-22-9 trans-2-(1-methyl-2-(prop-1-en-2-yl)cyclobutyl)ethanol 
• 26532-22-9 grandisol 

Relevant articles and documents

(-)-Grandisol, the antipode of the boll weevil pheromone, is biologically active

-

Utilization of Selenium-directed Cycloadditions: Concise Synthesis of (+/-)-Fragranol

The reaction of 2-(phenylseleno)prop-1-ene 1 and methyl vinyl ketone 2 in the presence of EtAlCl2 gave the cycloadducts 3a and 3b.A radical substitution of the adducts 3a and 3b with allyltributyltin gave the allylated cyclobutane product, which was transformed into the cyclobutane natural product, (+/-)-fragranol.Stereoselective radical substitution using the ethylene glycol ketals of compounds 3a and 3b was also achieved.

STEREOSELECTIVE TOTAL SYNTHESIS OF RACEMIC GRANDISOL. AN IMPROVED CONVENIENT PROCEDURE

(+/-) Grandisol has been stereoselectively synthesized in a 31 percent overall yield by a practical and convenient procedure employing the Salomon photobicyclization as the key-step.