55895-87-9Relevant articles and documents
Design, synthesis and anticancer mechanistic studies of linked azoles
Islam, Md. Amirul,Zhang, Yuqi,Wang, Yao,McAlpine, Shelli R.
supporting information, p. 300 - 305 (2015/03/30)
Herein we report the synthesis and biological activity evaluation of 2,4 linked azole-containing molecules. A total of 13 linked thiazole- and oxazole-containing compounds were synthesized in good yields. Cytotoxicity evaluation of those compounds showed
Mechanistic studies of sanguinamide B derivatives: A unique inhibitor of eukaryotic ribosomes
Tantisantisom, Worawan,Ramsey, Deborah M.,McAlpine, Shelli R.
supporting information, p. 4638 - 4641 (2013/10/08)
Described are mechanistic studies of two Sanguinamide B (San B) derivatives. These compounds were identified as eukaryotic ribosomal inhibitors. Two biotinylated San B derivatives were synthesized and used to capture protein targets in a pull-down assay.
Synthesis of new oxathiazinane dioxides and their in vitro cancer cell growth inhibitory activity
Borcard, Fran?oise,Baud, Matthias,Bello, Claudia,Dal Bello, Giovanna,Grossi, Francesco,Pronzato, Paolo,Cea, Michele,Nencioni, Alessio,Vogel, Pierre
supporting information; experimental part, p. 5353 - 5356 (2010/11/04)
New oxathiazinane dioxides derived from d- and l-serine have been tested for their in vitro cell growth inhibitory activity toward SKBR3 breast cancer cells. Compound (R)-24 (R′ = BrCH2C6H 4-C6H4CH2) showed a cytotoxicity with IC50 ≈ 10 μM.
