560121-52-0 Usage
Description
Cyenopyrafen is a new acaricide for use in fruit, vegetables, and tea. Its oral LD50 in rats is 2000 mg/kg. Cyenopyrafen is also an inhibitor of mitochondrial complex II (Lummen, 2007).
Uses
Cyenopyrafen is part of the pyrazole class of fungicides and insecticide acting on ticks.
Definition
ChEBI: Cyenopyrafen is a member of the class of pyrazoles that is ethene in which the hydrogens at position 1 have been replaced by p-tert-butylphenyl and cyano groups, while the hydrogens at position 2 have been replaced by pivaloyloxy and 1,3,4-trimethylpyrazol-5-yl groups (the E isomer). A proacaricide (by hydrolysis of the pivalate ester linkage to give the corresponding enol), it was formerly used for the control of mites in fruit, vegetables and tea. It has a role as a proacaricide and an agrochemical. It is a nitrile, a pivalate ester and a member of pyrazoles.
Toxicology
Cyenopyrafen and cyflumetofen have been shown to have very low toxicity to mammals, birds, bees and beneficial insects, including predatory mites. They have some toxicity to fish and aquatic invertebrates, but pose minimal risk because they are rapidly degraded in water and soil.
Mode of action
Cyenopyrafen and cyflumetofen are pro-insecticides that are metabolized to corresponding enol products that inhibit mitochondrial electron transport complex II, leading to rapid paralysis and death due to cellular energy starvation. Resistance has not yet been reported.
Check Digit Verification of cas no
The CAS Registry Mumber 560121-52-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,6,0,1,2 and 1 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 560121-52:
(8*5)+(7*6)+(6*0)+(5*1)+(4*2)+(3*1)+(2*5)+(1*2)=110
110 % 10 = 0
So 560121-52-0 is a valid CAS Registry Number.
InChI:InChI=1/C24H31N3O2/c1-15-16(2)26-27(9)20(15)21(29-22(28)24(6,7)8)19(14-25)17-10-12-18(13-11-17)23(3,4)5/h10-13H,1-9H3/b21-19-
560121-52-0Relevant articles and documents
Synthesis and acaricidal activity of cyenopyrafen and its geometric isome
Yu, Haibo,Xu, Man,Cheng, Yan,Wu, Hongfei,Luo, Yanmei,Li, Bin
, p. 26 - 34 (2012/03/26)
Cyenopyrafen and its geometric isomer were synthesized by various methods, and the structures were characterized by 1H NMR. 13C NMR, IR, elemental analyses and X-ray diffraction analyses. The bioassay tests showed that cyenopyrafen e
Process for producing acrylonitrile compound
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Page/Page column 6; 7, (2008/06/13)
There is provided a process for stereoselectively producing E-form of 3-acyloxyacrylonitrile compound (3) or Z-form which comprises reacting 3-oxopropionitrile compound (1) with an acid chloride (2), characterized in that the reaction is conducted with re
