264272-46-0

Usage

Uses

Used in Pesticide Industry:
2-(4-tert-butylphenyl)-3-hydroxy-3-(1,3,4-trimethyl-1H-pyrazol-5-yl)acrylonitrile is used as an intermediate in the preparation of Cyenopyrafen, a potent acaricide, for controlling mites and ticks in agricultural settings. Its role in the synthesis process is crucial for developing effective pest control solutions.

Upstream product

• 773136-70-2 methyl 1,3,4-trimethylpyrazole-5-carboxylate 
• 3288-99-1 4-tert-butylbenzyl cyanide 
• 615-79-2 ethyl 2,4-diketopentanoate 
• 4027-57-0 ethyl 5-methyl-2H-pyrazole-3-carboxylate 
• 5744-40-1 ethyl 1,3-dimethylpyrazole-5-carboxylate 
• 166313-45-7 1,3-dimethyl-4-chloromethylpyrazole-5-carboxylic acid ethyl ester 
• 89202-90-4 1-methyl-3-methyl-4-methyl-5-pyrazolecarboxylic acid ethyl ester 
• 115294-67-2 1,3,4-trimethyl-1H-pyrazole-5-carboxylic acid 
• 330937-69-4 1,3,4-trimethylpyrazole-5-carbonyl chloride 

Downstream Products

• 560121-52-0 (2E)-3-(2,2-dimethypropanoyloxy)-2-(4-tert-butylphenyl)-3-(1,3,4-trimethylpyrazol-5-yl)acrylonitrile 
• 560121-52-0 (2Z)-3-(2,2-dimethypropanoyloxy)-2-(4-tert-butylphenyl)-3-(1,3,4-trimethylpyrazol-5-yl)acrylonitrile 

Relevant academic research and scientific papers

PYRAZOLE DERIVATIVE

A pyrazole derivative having the following formula stru-1: The pyrazole derivative is used for prevention and control of pests.

A class of pyrazole derivatives, preparation method and application thereof (by machine translation)

The invention discloses a following formula stru - 1 indicated by the pyrazole derivatives, The definition of each substituent in the specification. This invention relates to pyrazole derivatives suitable for use in the pest. (by machine translation)

Design, Synthesis, and Acaricidal Activities of Novel Pyrazole Acrylonitrile Compounds

Using cyenopyrafen as the lead compound, a series of novel pyrazole acrylonitrile compounds were designed and synthesized via the reaction of butylphenylacetonitrile with the corresponding (substituted pyrazol-5-yl) methanone of pyrethroid alcohols in the presence of potassium tert-butoxide. These compounds showed prominent acaricidal activity against Tetranchus urticae. In particular, IIf, IIh, IIo, and IIp displayed excellent activities, which the median lethal concentrations were all lower 0.4 mg/L. In addition, the structure-activity relationship for the target compounds was discussed.

Acrylonitrile compound, and preparation method and application thereof

The invention discloses an acrylonitrile compound shown as the formula (I), and a preparation method and application thereof. Ar , Ar, R, W and Y in the formula (I) have definitions given in the description. The compound in the formula (I) has insec

Synthesis and acaricidal activity of cyenopyrafen and its geometric isome

Cyenopyrafen and its geometric isomer were synthesized by various methods, and the structures were characterized by 1H NMR. 13C NMR, IR, elemental analyses and X-ray diffraction analyses. The bioassay tests showed that cyenopyrafen e