56078-05-8

Basic information

• Product Name: Methyl-1-(2',2'-dimethoxyethyl)-cyclohexan-1-carboxylat
• Synonyms: Methyl-1-(2',2'-dimethoxyethyl)-cyclohexan-1-carboxylat
• CAS NO: 56078-05-8
• Molecular Weight: 230.304
• Mol File: 56078-05-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Methyl-1-(2',2'-dimethoxyethyl)-cyclohexan-1-carboxylat(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl-1-(2',2'-dimethoxyethyl)-cyclohexan-1-carboxylat(56078-05-8)
• EPA Substance Registry System: Methyl-1-(2',2'-dimethoxyethyl)-cyclohexan-1-carboxylat(56078-05-8)

Safety Data

• Hazardous Substances Data: 56078-05-8(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 41487-75-6 Methyl-1-(2',2'-dibrom-ethyl)-cyclohexan-1-carboxylat 
• 29800-45-1 spiro[3.5]nonan-1-one 
• 41487-74-5 2,2-Dibromospiro<3,5>nonan-1-on 
• 124-41-4 sodium methylate 
• 4630-82-4 methyl cyclohexylcarboxylate 

Downstream Products

• 825-04-7 methyl 1-methylcyclohexanecarboxylate 
• 41487-76-7 methyl 1-(2-oxoethyl)cyclohexane-1-carboxylate 

Relevant articles and documents

Synthesis of functionalized γ-lactone via Sakurai exo -cyclization/rearrangement of 3,3-bis(silyl) enol ester with a tethered acetal

An efficient synthesis of functionalized γ-lactones has been developed involving Sakurai exo-cyclization/rearrangement of 3,3-bis(silyl) enol esters with a tethered acetal. While the steric and electronic effects of geminal bis(silane) favor the desired Sakurai pathway, the methoxy species formed in the deprotection step also facilitates both cyclization and rearrangement. The synthetic value of this approach has been demonstrated by efficiently transforming the E-vinylsilane into enyne and the γ-lactone moiety into multisubstituted THF.