56119-89-2Relevant articles and documents
Preparation method for pyrazole
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Paragraph 0011; 0012; 0013; 0014; 0015; 0016; 0129; 0130, (2017/08/26)
The invention relates to a preparation method for pyrazole, belonging to the field of organic chemistry. The preparation method disclosed in the invention realizes preparation of pyrazole through a cyclization reaction of N-alkylated phenylsulfonylhydrazone with terminal alkyne. The reaction has good function group tolerance and high yield and is applicable to a wide range of substrates.
Regioselective synthesis of 1,3,5-Trisubstituted Pyrazoles from N-Alkylated Tosylhydrazones and terminal Alkynes
Kong, Yuanfang,Tang, Meng,Wang, Yun
, p. 576 - 579 (2014/04/03)
An efficient synthesis of 1,3,5-trisubstituted pyrazoles from Nalkylated tosylhydrazones and terminal alkynes was developed. The protocol was applied to a wide range of substrates and demonstrated excellent tolerance to a variety of substituents, includin
Regioselective three-component synthesis of highly fluorescent 1,3,5-trisubstituted pyrazoles
Willy, Benjamin,Mueller, Thomas J. J.
experimental part, p. 4157 - 4168 (2009/05/11)
3,5-Disubstituted and 1,3,5-trisubstituted pyrazoles are readily synthesized from acyl chlorides, terminal alkynes, and hydrazines by a consecutive one-pot three-component Sonogashira coupling/Michael addition/cyclocondensation sequence in good to excelle