56153-57-2Relevant academic research and scientific papers
Site-specific functionalisation of proteins by a Staudinger-type reaction using unsymmetrical phosphites
Boehrsch, Verena,Serwa, Remigiusz,Majkut, Paul,Krause, Eberhard,Hackenberger, Christian P. R.
scheme or table, p. 3176 - 3178 (2010/09/04)
Unsymmetrical phosphites react efficiently in a Staudinger reaction with p-azido-phenylalanine, which can be applied for the biotinylation of proteins, thereby expanding the scope of the chemoselective Staudinger-phosphite reaction of aryl azides with symmetrical phosphites to the corresponding phosphoramidates. The Royal Society of Chemistry 2010.
Synthesis of New α-Ketophosphonates
Benech, Jm.,Coindet, M.,Manouni, D. El,Leroux, Y.
, p. 377 - 384 (2007/10/03)
Using the Arbuzov reaction, asymmetrical or symmetrical benzyl α-ketophosphonates can be synthesized.In the case of symmetrical benzyl α-ketophosphonates, it was observed that the modification of benzyl groups influences the yield of the Arbuzov reaction. - Keywords: α-ketophosphonate; benzyl groups; Arbuzov reaction
Phosphitylation via the Mitsunobu reaction
Grice, I. Darren,Harvey, Peta J.,Jenkins, Ian D.,Gallagher, Michael J.,Ranasinghe, Millagahamada G.
, p. 1087 - 1090 (2007/10/03)
Treatment of a dialkyl phosphite with triphenylphosphine and diisopropyl azodicarboxylate in toluene, followed by addition of an alcohol, results in the formation of the corresponding trialkyl phosphite. Similarly, dialkyl phosphonites can be synthesised from monoalkyl phosphites (alkyl phosphinates).
