Benzyl dimethyl phosphite

Base Information

• Chemical Name: Benzyl dimethyl phosphite
• CAS No.: 56153-57-2
• Molecular Formula: C9H13O3P
• Molecular Weight: 200.174
• DSSTox Substance ID: DTXSID10556922
• Nikkaji Number: J702.766D
• Wikidata: Q82438647
• Mol file: 56153-57-2.mol

Synonyms:benzyl dimethyl phosphite;56153-57-2;SCHEMBL383496;DTXSID10556922

Chemical Property of Benzyl dimethyl phosphite

Chemical Property:

• XLogP3: 1.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 200.06023127
• Heavy Atom Count: 13
• Complexity: 122

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COP(OC)OCC1=CC=CC=C1

Technology Process of Benzyl dimethyl phosphite

There total 4 articles about Benzyl dimethyl phosphite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

dimethyl N,N-diisopropylphosphoramidite (122194-07-4) + benzyl alcohol (100-51-6,185532-71-2) → benzyl dimethyl phosphite (56153-57-2)

Guidance literature:

With 1H-tetrazole; In acetonitrile; at 20 ℃;

DOI:10.1039/b926818a

Reference yield: 60.0%

benzyl alcohol (100-51-6,185532-71-2) + dimethyl chlorophosphite (3743-07-5) → benzyl dimethyl phosphite (56153-57-2)

Guidance literature:

With triethylamine; at 100 ℃; for 4h;

Reference yield:

Dimethyl phosphite (868-85-9) + benzyl alcohol (100-51-6,185532-71-2) → benzyl dimethyl phosphite (56153-57-2)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; Multistep reaction; 1.) toluene, 0 deg C; 2.) toluene, 40 deg C, 24 h;

DOI:10.1016/0040-4039(95)02282-1

upstream raw materials:

Dimethyl phosphite

benzyl alcohol

dimethyl chlorophosphite

dimethyl N,N-diisopropylphosphoramidite

Downstream raw materials:

dimethyl ethylphosphonate

1,1'-(1,2-ethanediyl)bisbenzene

C₂₆H₂₇N₂O₇P

C₃₂H₃₁N₂O₇P