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CYCLOPROPANECARBOXYLIC ACID, 1-ACETYL- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

56172-71-5

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56172-71-5 Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 40, p. 2969, 1975 DOI: 10.1021/jo00908a030

Check Digit Verification of cas no

The CAS Registry Mumber 56172-71-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,1,7 and 2 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 56172-71:
(7*5)+(6*6)+(5*1)+(4*7)+(3*2)+(2*7)+(1*1)=125
125 % 10 = 5
So 56172-71-5 is a valid CAS Registry Number.
InChI:InChI=1/C6H8O3/c1-4(7)6(2-3-6)5(8)9/h2-3H2,1H3,(H,8,9)

56172-71-5Relevant academic research and scientific papers

CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES

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Page/Page column 280, (2021/07/02)

The invention relates to compounds of formula (I) and to their use in treating or preventing an inflammatory disease or a disease associated with an undesirable immune response: (I) wherein, RA1, RA2, RC and RD are as defined herein.

Preparation method and application of Marizomib key intermediate

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Paragraph 0073-0076, (2020/07/02)

The invention belongs to the field of chemical synthesis, particularly relates to a preparation method and application of a Marizomib key intermediate, and particularly relates to a preparation methodof a Marizomib key intermediate. Natural L-serine is selected as an initial raw material, and an obtained serine fragment protected by a functional group is connected with a 1, 3-dicarbonyl cyclopropyl compound so that the Marizomib key intermediate (a skeleton structure) is prepared, and the preparation method is high in preparation efficiency and yield, safer and more environmentally friendly.Then, the prepared Marizomib key intermediate is used for producing Marizomib, and the Marizomib is obtained through intramolecular cyclization reaction and group modification, protective group removal and structural modification in sequence. Besides, the low-toxicity solvent is used in the whole synthesis process, reagents with high toxicity and difficult preparation are avoided, the solvent consumption is low, the target product recovery rate is high and the stability is good.

ILLUDIN ANALOGS, USES THEREOF, AND METHODS FOR SYNTHESIZING THE SAME

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Page/Page column 14, (2020/03/29)

This invention provides illudin derivatives, intermediates, preparation methods, pharmaceutical compositions and uses thereof. Specific examples include novel synthetic routes to prepare illudin derivatives and an illudin derivative having a positive optical rotation, which has therapeutic value.

COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS

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Page/Page column 637; 638, (2015/02/02)

The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.

THIAZOLE DERIVATIVE

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Page/Page column 160, (2012/12/14)

Provided is a compound having an agonist action on GPR52, which is useful as a prophylactic or therapeutic drug for mental diseases such as schizophrenia and the like, and the like. A compound represented by the formula (I): wherein each symbol is as defi

BIS-PYRIDYLPYRIDONES AS MELANIN-CONCENTRATING HORMONE RECEPTOR 1 ANTAGONISTS

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Page/Page column 25, (2010/12/29)

The invention provides novel bis-pyridylpyridones which are antagonists at the melanin-concentrating hormone receptor 1 (MCHR1 ), pharmaceutical compositions containing them, processes for their preparation, and their use in therapy and for the treatment

Spiro compound

-

, (2008/06/13)

The present invention relates to spiro compounds of general formula I: STR1 wherein the substituents are herein below defined. The present invention relates to antibacterial spiro compounds which are of value as drugs for humans, veterinary drugs or drugs for use in fish culture or as preservatives, and to antibacterial compositions containing one or more of the same compounds as active ingredients.

Tandem Cyclization-Cycloaddition Reaction of Rhodium Carbenoids. Studies Dealing with the Geometric Requirements of Dipole Formation

Padwa, Albert,Chinn, Richard L.,Hornbuckle, Susan F.,Zhang, Zhijia J.

, p. 3271 - 3278 (2007/10/02)

The carbenoid intermediate derived by the treatment of several 1-diazabutadienediones with rhodium(II) acetate undergoes ready transannular cyclization onto the neighboring keto group to give five-membered ring carbonyl ylides.The dipole derived from ethy

Preparation and Cleavage of Some Cyclopropane Derivatives

Podder, Ranjan Kumar,Sarkar, Ranjit Kumar,Ray, Suvas C.

, p. 530 - 536 (2007/10/02)

Alkylation of active methylene compounds with 1,2-dibromoethane using anhyd.K2CO3/DMF at room temperature gives cyclopropane derivatives which undergo selective transformation by simple methods.Cyclopropanes, obtained by the condensation of α-diazoacetophenones with olefins, are cleaved to trisubstituted olefins with Grignard reagent.Hydration of the products has also been studied.

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