562823-72-7

Upstream product

• 562823-58-9 2-((4S,5S)-5-((benzyloxy)methyl)-2,2-dimethyl-1,3-dioxolan-4-yl)acetaldehyde 
• 1730-25-2 allylmagnesium bromide 
• 562823-57-8 [2-((4S,5S)-5-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethoxy]-tert-butyl-diphenyl-silane 
• 562823-69-2 (2R,3S)-5-(tert-Butyl-diphenyl-silanyloxy)-2,3-dihydroxy-pentanoic acid ethyl ester 
• 562823-70-5 (4R,5S)-5-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid ethyl ester 
• 562823-56-7 {(4S,5S)-5-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-methanol 
• 562823-71-6 2-((4S,5S)-5-(benzyloxymethyl)-2,2-dimethyl-1,3-dioxolan-4-yl)ethanol 
• 256494-25-4 (E)-ethyl 5-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)pent-2-enoate 
• 100-39-0 benzyl bromide 

Downstream Products

• 562823-66-9 (2S,3S,5S)-6-((4S,5S)-5-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-5-(tert-butyl-dimethyl-silanyloxy)-2,3-dihydroxy-hexanoic acid methyl ester 
• 562823-65-8 (Z)-(S)-6-((4S,5S)-5-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-5-(tert-butyl-dimethyl-silanyloxy)-hex-2-enoic acid methyl ester 
• 562823-60-3 Acrylic acid (S)-1-((4S,5S)-5-benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl)-but-3-enyl ester 
• 562823-61-4 (S)-6-((4S,5S)-5-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl)-5,6-dihydro-pyran-2-one 
• 562823-59-0 (S)-1-((4S,5S)-5-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-pent-4-en-2-ol 
• 1054661-39-0 1-((4S,5S)-5-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-pent-4-en-2-one 

Relevant academic research and scientific papers

An enantioselective synthesis of the C1-C9 segment of antitumor macrolide peloruside A

A stereocontrolled synthesis of the C1-C9 segment of the marine natural product peloruside A is described. The key steps involve Sharpless's catalytic asymmetric dihydroxylation reaction, a chelation-controlled reduction of chiral β-alkoxy ketones to elaborate the syn-1,3-diol functionality and a ring-closing olefin metathesis of a homoallylic alcohol-derived acrylate ester to form an α,β-unsaturated δ-lactone.