5635-98-3

Usage

Uses

Used in Pharmaceutical Industry:
2-Methoxy-methylphenol is used as a precursor in the synthesis of various pharmaceuticals for its versatile chemical properties.
Used in Flavor and Fragrance Industry:
2-Methoxy-methylphenol is used as a component in the production of flavorings and fragrances due to its distinctive smoky, spicy odor.
Used in Disinfection:
2-Methoxy-methylphenol is used as a disinfectant for its antimicrobial properties.
Used in Polymer Production:
2-Methoxy-methylphenol is used as a precursor to various polymers for its ability to contribute to the formation of polymer chains.
Used in Chemical Reactions:
2-Methoxy-methylphenol is used as a reagent in various chemical reactions, including as a source of the methoxy functional group.
Used in Aromatic Compound Synthesis:
2-Methoxy-methylphenol is used in the synthesis of other aromatic compounds for its ability to participate in aromatic substitution and formation reactions.
Used in Dye and Resin Manufacturing:
2-Methoxy-methylphenol is used as an intermediate in the manufacture of dyes and resins for its role in creating complex organic molecules.

InChI:InChI=1/C11H9ClN2O2/c1-7-10(6-15)11(16)14(13-7)9-4-2-8(12)3-5-9/h2-6,13H,1H3

Upstream product

• 67-56-1 methanol 
• 90-01-7 salicylic alcohol 
• 62723-78-8 2-methoxymethylaniline 
• 10419-28-0 2,2-diphenylchromane 
• 553-86-6 benzofuran-2(3H)-one 
• 27890-67-1 6-methylene-cyclohexa-2,4-dienone 
• 124-41-4 sodium methylate 
• 145914-45-0 C₁₉H₁₁NO₇ 
• 144222-44-6 C₂₁H₁₁Cl₂NO₆ 
• 153046-41-4 C₂₁H₁₆O₆S 
• 152941-46-3 C₂₁H₁₆O₇ 
• 152936-41-9 C₂₁H₁₂Cl₂O₄ 
• 74-88-4 methyl iodide 
• 50-00-0 formaldehyd 

Downstream Products

• 27890-67-1 6-methylene-cyclohexa-2,4-dienone 
• 53565-75-6 4-(phenylimino-methyl)-phenol 
• 90-01-7 salicylic alcohol 
• 930-73-4 1-methyl pyridinium iodide 
• 4167-75-3 2-isobutylphenol 
• 136-81-2 2-pentylphenol 
• 827-80-5 1-ethoxymethoxy-2-methylbenzene 
• 96850-25-8 2-tridecylphenol 
• 675855-54-6 1-ethoxymethoxy-2-isobutyl-benzene 
• 675855-52-4 1-ethoxymethoxy-2-pentyl-benzene 
• 675855-59-1 2-(2-methylpropyl)phenyl trifluoromethanesulfonate 
• 675855-53-5 1-ethoxymethoxy-2-tridecyl-benzene 
• 675855-58-0 2-tridecylphenyl trifluoromethanesulfonate 
• 95-48-7 ortho-cresol 

Relevant academic research and scientific papers

Fabricating Bifunctional Co?Al2O3@USY Catalyst via In-Situ Growth Method for Mild Hydrodeoxygenation of Lignin to Naphthenes

To enhance the catalytic activity and stability of metal catalysts in the hydrodeoxygenation of lignin derivatives into naphthenes, a bifunctional Co?Al2O3@USY catalyst was fabricated by the reduction of CoAl layered double hydroxide in-situ grown on the USY zeolite. In the hydrodeoxygenation of guaiacol, a 100.0 % conversion with cyclohexane yield up to 93.6 % was achieved at 180 °C, 3 MPa for 4 h, which should be the hitherto lowest reaction temperature that has been reported over Co-based metal catalysts. This catalyst was also relatively stable with 5 runs and exhibited excellent catalytic performance in the hydrodeoxygenation of other lignin model compounds and even real lignin feedstock into naphthenes. The high-efficiency of Co?Al2O3@USY was attributed to the synergistic effect between well-dispersed small Co nanoparticles and abundant acidic sites on the USY surface, while the outstanding stability was attributed to the anchoring effect of Al2O3 matrix to Co nanoparticles which avoided the leaching of Co species and particle agglomeration. This work provides a potential strategy for the design of an efficient and stable catalyst for lignin utilization.

Diazaborines oxidize slowly with H2O2 but rapidly with peroxynitrite in aqueous buffer

Reactive oxygen species (ROS) such as hydrogen peroxide (H2O2) and peroxynitrite (ONOO?) oxidize arylboronic acids to their corresponding phenols. When used in molecular imaging probes and in ROS-responsive molecules, however, simple arylboronic acids struggle to discriminate between H2O2 and ONOO? because of their fast rate of reaction with both ROS. Here, we show that diazaborines (DABs) react slowly with H2O2 but rapidly with peroxynitrite in an aqueous buffer. In addition to their slow reaction with H2O2, the immediate product of DAB oxidation with H2O2 and ONOO? can yield a kinetically trapped CN Z-isomer that slowly equilibrates with its E-isomer. Taken together, our work shows that diazaborines exhibit enhanced kinetic discrimination between H2O2 and ONOO? compared to arylboronic acids, opening up new opportunities for diazaborine-based tools in chemical biology.

A naphthoquine phosphate process impurity and its synthesis method

The invention discloses a compound of formula (I) reported shown naphthoquine phosphate has not seen the structure of process impurities, and provides a alkyl aminomethyl phenol is converted into the corresponding alkyl ethoxy methyl phenol, or substitute

A cascade mechanism for a simple reaction: The gas-phase methylation of phenol with methanol

The gas-phase alkylation of phenol with methanol, a reaction triggered for the production of o-cresol and 2,6-xylenol, is catalysed by MgO-based catalysts. Despite the industrial use of this process, the mechanism of the reaction – which is commonly believed to be based on a classical electrophilic attack of activated methanol onto the aromatic ring – is far from being fully understood. In some previous studies we reported that the reaction intermediate is salicylic alcohol, which is formed by the reaction between the adsorbed phenolate and formaldehyde, the latter being formed in-situ by methanol dehydrogenation. Here we elucidate the following steps of the reaction mechanism, by combining reactivity experiments and DFT calculation, with MgO as a model catalyst. It was found that salicylic alcohol dehydrates into quinone methide, which is then reduced via H-transfer by methanol to o-cresol. Moreover, a dehydrogenation/hydrogenation equilibrium is established between salicylic alcohol and salicylic aldehyde. The methide can also react with methanol to form 2-methoxymethylphenol, which may decompose into o-cresol, thus providing an alternative pathway for the formation of the alkylated compound.

PROCESS FOR THE PREPARATION OF 2-METHOXYMETHYL-1,4-BENZENEDIAMINE, ITS DERIVATIVES THEREOF AND THE SALTS THEREOF

A process for synthesizing 2-methoxymethyl-1,4-benzenediamine, its derivatives of formula (IV) and the salts thereof, which comprises a reductive amination step. The preferred final product is 2-methoxymethyl-1,4-benzenediamine of formula (IV-a). (Formula

Mild and rapid method for the generation of ortho -(naphtho)quinone methide intermediates

A new mild method has been devised for generating o-(naphtho)quinone methides via fluoride-induced desilylation of silyl derivatives of o-hydroxybenzyl(or 1-naphthylmethyl) nitrate. The reactive o-(naphtho)quinone methide intermediates were trapped by C,

Copper(I)-catalyzed hydroalkoxylation/hydrogen-bonding-induced asymmetric hetero-diels-alder cycloaddition cascade: An approach to aromatic spiroketals

One thing leads to another: Bis(benzannelated) 5,6-spiroketal skeletons can be constructed by an efficient cascade process involving an unprecedented CuI-catalyzed intramolecular alkyne hydroalkoxylation and an asymmetric hetero-Diels-Alder cyc

Substituted triazole derivatives as oxytocin antagonists

The present invention relates to substituted triazoles of formula (I), uses thereof, processes for the preparation thereof and compositions containing said compounds. These inhibitors have utility in a variety of therapeutic areas including sexual dysfunction.

Rare earth metal trifluoromethanesulfonates catalyzed benzyl-etherification.

Rare earth metal trifluoromethanesulfonates [rare earth metal triflate, RE(OTf)3] were found to be efficient catalyst for benzyl-etherification. In the presence of a catalytic amount of RE(OTf)3, condensation of benzyl alcohols and aliphatic alcohols proceeded smoothly to afford the benzyl ethers. The condensation between benzyl alcohols and thiols also proceeded, and thio ethers were obtained in good yield. In these reactions, RE(OTf)3 could be recovered easily after the reactions were completed and could be reused without loss of activity.