5652-27-7

Upstream product

• 98-09-9 benzenesulfonyl chloride 
• 7647-01-0 hydrogenchloride 
• 64-18-6 formic acid 
• 302-72-7 rac-Ala-OH 

Downstream Products

• 124-38-9 carbon dioxide 
• 882-33-7 diphenyldisulfane 
• 1093379-05-5 N-(1,6-dimethyl-2-oxo-3-oxaheptanyl)benzenesulphonamide 
• 1093379-09-9 N-(1,5-dimethyl-2-oxo-3-oxahexanyl)benzenesulphonamide 
• 105617-39-8 C₉H₁₀ClNO₃S 
• 1093379-13-5 N-(1,4-dimethyl-2-oxo-3-oxapentanyl)benzenesulphonamide 
• 1093379-17-9 N-(1,4,4-trimethyl-2-oxo-3-oxapentanyl)benzenesulphonamide 
• 1313238-70-8 N-[1-(3-methyl-4-oxo-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-7-yl)ethyl]benzenesulfonamide 
• 777949-58-3 N-[3-(phenylseleno)prop-2-ynyl]-2-[(phenylsulfonyl)amino]propanamide 

Relevant academic research and scientific papers

New peptide derived antimalaria and antimicrobial agents bearing sulphonamide moiety

Fourteen novel dipeptide carboxamide derivatives bearing benzensulphonamoyl propanamide were synthesized and characterized using 1H NMR, 13C NMR, FTIR and MS spectroscopic techniques. In vivo antimalarial and in vitro antimicrobial studies were carried out on these synthesized compounds. Molecular docking, haematological analysis, liver and kidney function tests were also evaluated to assess the effect of the compounds on the organs. At 200 mg/kg body weight, 7i inhibited the multiplication of the parasite by 81.38% on day 12 of post-treatment exposure. This was comparable to the 82.34% reduction with artemisinin. The minimum inhibitory concentration (MIC) in μM ranged from 0.03 to 2.34 with 7h having MIC of 0.03 μM against Plasmodium falciparium. The in vitro antibacterial activity of the compounds against some clinically isolated bacteria strains showed varied activities with some of the new compounds showing better activities against the bacteria and the fungi more than the reference drug ciprofloxacin and fluconazole.

ZnO and ZnO-nanoparticles: Efficient and reusable heterogeneous catalysts for one-pot synthesis of N-acylsulfonamides and sulfonate esters

Commercially available and preparative ZnO nanoparticles are reported as efficient and reusable catalysts for the chemoselective synthesis of N-acylsulfonamides and sulfonate esters. A one-pot sequential sulfonylation and acylation of amines took place to afford the N-acylsulfonamides in excellent yields under solvent-free conditions. The ZnO catalyst can be reused for without significant loss of catalytic activity.

Synthesis of some sulphonamide insect juvenile hormone - Part I

Regular use of classical insecticides has drastically effected the environment and warm blooded animals. Therefore, there is an urgent need to look for a kind of chemicals which are very specific, targeted in their action and environment friendly. Since l