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Usage

Uses

Used in Pharmaceutical Industry:
Normacromerine is used as a pharmaceutical compound for its potential therapeutic applications. Its unique structure and properties make it a promising candidate for the development of new drugs targeting various health conditions.
Used in Chemical Research:
Normacromerine is used as a research compound in the field of chemistry, particularly in the study of alkaloids and their potential applications. Its structure and properties can provide valuable insights into the development of new chemical compounds and their potential uses.
Used in Plant Biology:
Normacromerine is used in plant biology as a marker compound for the Coryphantha macromeris species. Its presence in the plant can help researchers understand the plant's biochemistry and its potential interactions with other organisms.

References

Keller, McLaughlin., J. Pharm. Sci., 61, 147 (1972)

InChI:InChI=1/C11H17NO3/c1-12-7-9(13)8-4-5-10(14-2)11(6-8)15-3/h4-6,9,12-13H,7H2,1-3H3

Upstream product

• 64-17-5 ethanol 
• 74-89-5 methylamine 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 40511-15-7 1-(3,4-dimethoxy-phenyl)-2-methylamino-ethanone; hydrochloride 
• 6309-18-8 2-(3,4-dimethoxyphenyl)-2-hydroxyacetonitrile 
• 6924-15-8 2-amino-1-(3,4-dimethoxy-phenyl)-ethanol 
• 33342-73-3 α-(N-methyl-N-benzylamino)-3,4-dimethoxyacetophenone 
• 1835-02-5 2-Bromo-1-(3,4-dimethoxyphenyl)ethanone 
• 91-16-7 1,2-dimethoxybenzene 
• 74-88-4 methyl iodide 
• 345231-54-1 N-methyl-N-benzyl-2-(3,4-dimethoxyphenyl)-2-hydroxyethylamine 
• 99986-87-5 3,4-dimethoxy-DL-mandelic acid-methylamide 

Downstream Products

• 74-89-5 methylamine 
• 107412-18-0 (+/-)-2-(acetyl-methyl-amino)-1-(3,4-dimethoxy-phenyl)-ethanol 

Relevant academic research and scientific papers

Reagents for Storage and Regeneration of Nonstabilized Azomethine Ylides: Spiroanthraceneoxazolidines

Nonstabilized azomethine ylides are easily trapped by anthraquinone to form stable spiro-oxazolidines, which have an unusual ability to undergo a cycloreversion in the presence of other dipolarophiles at 120-150°C. All tested recycloadditions with carbonyl compounds and electron-poor alkenes occurred in moderate to high yields (41-92%). Moreover, increasing the reaction temperature to 210°C made it possible to obtain adducts with low reactive dipolarophiles.

A simple two-step synthesis of 2-(alkylamino)-1-arylethanols, including racemic adrenaline, from aromatic aldehydes via 5-aryloxazolidines

Benzaldehydes react smoothly with nonstabilized azomethine ylides, generated in situ from sarcosine/formaldehyde or N-(methoxymethyl)-N- (trimethylsilylmethyl)benzylamine, to give 5-aryloxazolidines as intermediates. These were converted into 2-(alkylamino)-1-arylethanols in good yields by simple heating in methanol with hydrochloric acid, or by treatment with hydrazine hydrate in ethanol.

PROCESS FOR PREPARING N-METHYL-3, 4-DIMETHOXYPHENYLETHYLAMINE

Provided are intermediates useful for the preparation of verapamil and methods for their preparation.

Di- and tri-substituted oxazolidin-2-one oximes

Certain di- and tri- substituted oxazolidin-2-one oximes have antidepressant activity in warm blooded animals. Exemplary is 4-methyl-5-phenyl-2-oxazolidinone oxime.