5711-72-8

Basic information

• Product Name: 5-PYRIDIN-2-YL-1,3,4-OXADIAZOL-2-YLAMINE
• Synonyms: TIMTEC-BB SBB005501;4-oxadiazole,2-amino-5-(2-pyridyl)-3;2-AMINO-5-(2-PYRIDYL)-1,3,4-OXADIAZOLE;2-(5-AMINO-1,3,4-OXADIAZOL-2-YL)PYRIDINE;5-PYRIDIN-2-YL-1,3,4-OXADIAZOL-2-YLAMINE;5-pyridin-2-yl-1,3,4-oxadiazol-2-amine;5-(2-Pyridyl)-1,3,4-oxadiazol-2-amine;[5-(2-pyridyl)-1,3,4-oxadiazol-2-yl]amine
• CAS NO: 5711-72-8
• Molecular Formula: C₇H₆N₄O
• Molecular Weight: 162.15
• Mol File: 5711-72-8.mol
• Article Data: 7

Chemical Properties

• Melting Point: 265-268°C
• Boiling Point: 373.1 °C at 760 mmHg
• Flash Point: 179.5 °C
• Appearance: /
• Density: 1.357 g/cm³
• Vapor Pressure: 9.17E-06mmHg at 25°C
• Refractive Index: 1.614
• PKA: -1.08±0.19(Predicted)
• CAS DataBase Reference: 5-PYRIDIN-2-YL-1,3,4-OXADIAZOL-2-YLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-PYRIDIN-2-YL-1,3,4-OXADIAZOL-2-YLAMINE(5711-72-8)
• EPA Substance Registry System: 5-PYRIDIN-2-YL-1,3,4-OXADIAZOL-2-YLAMINE(5711-72-8)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 5711-72-8(Hazardous Substances Data)

Usage

General Description

5-Pyridin-2-yl-1,3,4-oxadiazol-2-ylamine is a synthetic compound that belongs to the class of organic compounds known as dialkylarylamines. Its structure includes a pyridine ring and an oxadiazole ring, which are connected by a nitrogen atom. The compound has proven interesting to researchers due to its potential use in the pharmaceutical industry, specifically in developing drugs for various diseases. Currently, it isn't commonly found in nature and is primarily created in a laboratory for research purposes. More extensive studies are required to fully understand its potential applications and safety.

InChI:InChI=1/C7H6N4O/c8-7-11-10-6(12-7)5-3-1-2-4-9-5/h1-4H,(H2,8,11)

Upstream product

• 13370-79-1 2-(pyridin-2-ylmethylidene)hydrazinecarboxamide 
• 1121-60-4 pyridine-2-carbaldehyde 
• 1452-63-7 picolinic acid hydrazide 
• 506-68-3 bromocyane 
• 61043-10-5 (E)-2-(pyridin-2-ylmethylene)hydrazinecarbothioamide 
• 98-98-6 2-Picolinic acid 
• 4426-72-6 hydrazine carboxamide 
• 4923-12-0 (2-picoloylcarbonyl)thiosemicarbazone 

Relevant articles and documents

New 1,3,4-oxadiazolecopper(II) derivatives obtained from thiosemicarbazone complexes

Pyridine-2-carbaldehyde thiosemicarbazone and pyridine-2-carbaldehyde 4N-methyl thiosemicarbazone ligands (HLI and HLImm respectively) undergo an oxidative cyclization when treated with bromate or iodate, leading to 2-amino-5-pyridin

Synthesis of 2-amino-1,3,4-oxadiazoles and 2-Amino-1,3,4-thiadiazoles via sequential condensation and I2-mediated oxidative C-O/C-S bond formation

2-Amino-substituted 1,3,4-oxadiazoles and 1,3,4-thiadiazoles were synthesized via condensation of semicarbazide/thiosemicarbazide and the corresponding aldehydes followed by I2-mediated oxidative C-O/C-S bond formation. This transition-metal-free sequential synthesis process is compatible with aromatic, aliphatic, and cinnamic aldehydes, providing facile access to a variety of diazole derivatives bearing a 2-amino substituent in an efficient and scalable fashion.

A green approach for the synthesis of biologically active heterocyclic compounds at the platinum electrode

In the present study, 2-amino-5-substituted-1,3,4-oxadiazoles (4a-k) have been synthesized by the electrochemical oxidation of semicarbazone (3a-k) using platinum anode at room temperature under controlled potential electrolysis in an undivided cell assem