57790-32-6

Upstream product

• 100-52-7 benzaldehyde 
• 75-77-4 chloro-trimethyl-silane 
• 121508-78-9 3-Iminobenzyl-1-propin 

Downstream Products

• 57735-02-1 [1-Phenyl-meth-(E)-ylidene]-(1-trimethylsilanylethynyl-pentyl)-amine 
• 69355-11-9 hex-5-yne-1,4-diamine 
• 57735-01-0 (1-Methyl-3-trimethylsilanyl-prop-2-ynyl)-[1-phenyl-meth-(E)-ylidene]-amine 
• 57790-33-7 [1-Phenyl-meth-(E)-ylidene]-(1-trimethylsilanylethynyl-but-3-ynyl)-amine 
• 57735-00-9 methyl 4-(benzylideneamino)-6-(trimethylsilyl)-5-hexynoate 

Relevant academic research and scientific papers

Synthesis of 3-amino-3-vinylpropanoic acid and its conversion to 4-amino-5-hydroxy-4,5-dihydrofuran-2-one hydrochloride (HAD), a cyclic stabilised form of aspartate 1-semialdehyde hydrochloride

3-amino-3-vinylpropanoic acid hydrochloride 4 was obtained from 4-acetoxyazetidin-2-one 1 in 3 steps. The ozonolysis of 4 yielded 3-amino-4-oxopropanoic acid hydrochloride (aspartate 1-semialdehyde hydrochloride 6). This labile α-aminoaldehyde is isolated

Method for preparation of sphingoid bases

The present invention provides a series of non-toxic compounds which function to inhibit the activity of S-1-P aldolase in respect to its cleavage of S-1-P. These inhibitors are described by the compounds of formula I STR1 wherein R is a radical containing 1 to 15 carbon atoms, a halogen, or hydrocarbon, R' is an organic radical or hydrogen, and R" is --NH3+ or --NH--NH +, with the proviso that, when R is CH3 (CH)12 (CH=CH) and R' is hydrogen, R" is --NH--NH3+. A method for preparing such compounds, which may generally be described as 1-phosphate derivatives of compounds which include a 2-amino-1,3-alcohol radical is also disclosed.