32917-19-4

Usage

Uses

Used in Chemical Industry:
Cyclohex-1-ene-1-methylamine serves as a corrosion inhibitor, protecting materials from the damaging effects of corrosive agents, thereby extending the service life of equipment and structures.
Used as a Catalyst in Chemical Reactions:
In the realm of catalysis, cyclohex-1-ene-1-methylamine facilitates various chemical reactions, enhancing the efficiency and selectivity of industrial processes.
Used in Pharmaceutical Production:
Cyclohex-1-ene-1-methylamine is utilized in the synthesis of pharmaceuticals, contributing to the development of new medications and therapies.
Used in Rubber Chemicals Manufacturing:
cyclohex-1-ene-1-methylamine plays a role in the production of rubber chemicals, which are essential for the creation of various rubber-based products with specific properties.
Used in Agricultural Products:
Cyclohex-1-ene-1-methylamine is also employed in the production of agricultural products, potentially contributing to advancements in crop protection and enhancement.

InChI:InChI=1/C7H13N/c8-6-7-4-2-1-3-5-7/h4H,1-3,5-6,8H2

Upstream product

• 22546-81-2 cyclohex-1-enecarboxamide 
• 108-94-1 cyclohexanone 
• 4845-04-9 1-cyclohexene-1-methanol 
• 81304-91-8 2-Cyclohex-1-enylmethyl-isoindole-1,3-dione 
• 5330-61-0 1-nitromethyl-cyclohexene 
• 13048-17-4 cyclohex-2-enecarbonitrile 
• 1855-63-6 cyclohex-1-enecarbonitrile 
• 1453-24-3 1-ethylcyclohexene 

Downstream Products

• 91375-04-1 1-Cyclohex-1-enylmethyl-pyrrolidine-2,5-dione 
• 934667-61-5 2-(4-chloro-phenyl)-2-{cyclohex-1-enylmethyl-[(7-methoxy-2-oxo-2H-chromen-4-yl)-acetyl]-amino}-N-isopropyl-acetamide 
• 181507-34-6 Dithiocarbonic acid S-(5-benzyloxy-1-{[cyclohex-1-enylmethyl-(toluene-4-sulfonyl)-amino]-methyl}-pent-2-ynyl) ester O-(2,2-dimethyl-propyl) ester 
• 58714-92-4 1-(cyclohex-1-en-1-ylmethyl)-biguanide hydrochloride 
• 1325713-96-9 (Z)-ethyl 3-(cyclohex-1-en-1-ylmethylamino)-3-phenylacrylate 
• 583-60-8 2-Methylcyclohexanone 
• 122048-94-6 4,4-Dimethyl-6-methylamino-2'-methylene-bicyclohexyl-6-en-2-one 

Relevant academic research and scientific papers

Stereoselective Synthesis of C-Vinyl Glycosides via Palladium-Catalyzed C?H Glycosylation of Alkenes

C-vinyl glycosides are an important class of carbohydrates and pose a unique synthetic challenge. A new strategy has been developed for stereoselective synthesis of C-vinyl glycosides via Pd-catalyzed directed C?H glycosylation of alkenes with glycosyl chloride donors using an easily removable bidentate auxiliary. Both the γ C?H bond of allylamines and the δ C?H bond of homoallyl amine substrates can be glycosylated in high efficiency and with excellent regio- and stereoselectivity. The resulting C-vinyl glycosides can be further converted to a variety of C-alkyl glycosides with high stereospecificity. These reactions offer a broadly applicable method to streamline the synthesis of complex C-vinyl glycosides from easily accessible starting materials.

Pd-Catalyzed Remote Site-Selective and Stereoselective C(Alkenyl)-H Alkenylation of Unactivated Cycloalkenes

A palladium-catalyzed alkenylation involving remote δ-position C(alkenyl)-H activation of cycloalkenes reacting with electron-deficient alkenes is described. This method features excellent site selectivity and stereoselectivity to efficiently afford only E-selective highly substituted 1,3-diene derivatives with extra-ligand-free and good functional group tolerance including estrone and free N-H tryptamine under weakly alkaline conditions. Mechanistic studies suggest that picolinamide as a bidentate directing group enables the formation of unique alkenyl palladacycle intermediates.

Regioselective intramolecular Markovnikov and anti-Markovnikov hydrofunctionalization of alkenes: Via photoredox catalysis

Highly regioselective Markovnikov hydrofunctionalization of alkenes was successfully realized via photoredox catalysis by introducing a urea group and fine tuning the hydrogen atom transfer catalysts. The anti-Markovnikov hydroamination of alkenes was also achieved with high yields and stereoselectivities in this work.

Domino Aryne Annulation via a Nucleophilic-Ene Process

1,2-Benzdiyne equivalents possess the unique property that they can react with two arynophiles through iteratively generated 1,2- and 2,3-aryne intermediates. Upon rational modification on the second leaving group of these aryne precursors, a domino aryne annulation approach was developed through a nucleophilic-ene reaction sequence. Various benzo-fused N-heterocyclic frameworks were achievable under transition metal-free conditions with a broad substrate scope.

Catalytic Multisite-Selective Acetoxylation Reactions at sp2 vs sp3 C-H Bonds in Cyclic Olefins

The first Pd-catalyzed multisite-selective acetoxylation reactions are disclosed at an unactivated alkene sp2 C-H bond versus secondary allylic sp3 C-H bond in cyclic olefins via the modulation of directing groups. The different directing groups overcome the key challenge in differentiating C-H bonds and provide a new controlling approach for site-specific C-H activation. A wide variety of substrates are readily acetoxylated under operationally simple conditions. Mechanistic studies suggest that different Pd (IV) intermediates were involved in the multisite-selective acetoxylation reactions.

Preparing method of 1-cyclohexene ethylamine

The invention discloses a preparing method of 1-cyclohexene ethylamine. 1-cyclohexene acetonitrile serves as a raw material for catalytic hydrogenation, a catalyst is one or two of hafnium, vanadium and niobium, the particle size of the catalyst is 10-20mm, reaction temperature is 1200-1300 DEG C, reaction pressure is 1.1-1.2MPa, a reaction stirring speed is 500 revolutions/minute, reaction time is 2.0-3.0h, under the reaction conditions, the yield of the 1-cyclohexene ethylamine is 70% or more, the method is simple in step and easy to operate, a reaction system is high in safety performance, processing cost is low, the yield is higher and economic values are better.

(2-hydroxy)ethyl-thioureas useful as modulators of alpha2B adrenergic receptors

Compounds of formula (i) and of formula (ii) wherein the symbols have the meaning disclosed in the specification, specifically or selectively modulate α2B and/or α2C adrenergic receptors in preference over α2A adrenergic receptors, and as such are useful for alleviating chronic pain and allodynia and have no or only minimal cardivascular and/or sedatory activity.

Photo-Aza-Claisen Rearrangements of Cyclic Enaminones

Cyclic enaminoes 1-7 were prepared and photolyzed.Compounds 1-4 reacted as expected to provide aza-De Mayo products 10 and 11, whereas 5 provided enaminone 12 in a novel photo-aza-Claisen rearrangement.Compounds 6 and 7 gave photo-aza-Claisen products 13 and 16, respectively, along with aza-De Mayo product 15 and 2 + 2 cycloaddition product 17, respectively.

Photochemistry of Succinimides with a Cycloalkenylalkyl Group in the Side Chain. Competitive Norrish Type II and Paterno-Buchi Reactions

Photolysis of N-succinimides (9c-f) (m>/=2) afforded mainly azepinediones (13c-f) with ring enlargement as the Norrish type II cyclization products.In the case of m=1, spiro-azepinedione derivatives (11a, b) were obtained in addition to tricyclic nitrogen heterocycles (10a, b), the Norrish type II products.These spiro-azepinediones are probably formed via imide imide-oxetanes by the intramolecular Paterno-Buchi reaction of these succinimides in competition with the type II processes.Keywords: N-succinimide; Norrish type II reaction; oxetane formation; azepinedione; spiro compound; photochemistry.