32917-19-4

Basic information

• Product Name: cyclohex-1-ene-1-methylamine
• Synonyms: cyclohex-1-ene-1-methylamine;1-Cyclohexene-1-(methanamine);1-Cyclohexenylmethylamine;(cyclohex-1-en-1-ylmethyl)amine(SALTDATA: HCl);(1-cyclohexen-1-ylMethyl)aMine hydrochloride (SALTDATA: HCl);Cyclohex-1-en-1-ylmethanamine
• CAS NO: 32917-19-4
• Molecular Formula: C₇H₁₃N
• Molecular Weight: 111.18482
• EINECS: 251-293-9
• Mol File: 32917-19-4.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 159°C at 760 mmHg
• Flash Point: 51.4°C
• Appearance: /
• Density: 0.907g/cm³
• Vapor Pressure: 2.55mmHg at 25°C
• Refractive Index: 1.491
• PKA: 10.62±0.29(Predicted)
• CAS DataBase Reference: cyclohex-1-ene-1-methylamine(CAS DataBase Reference)
• NIST Chemistry Reference: cyclohex-1-ene-1-methylamine(32917-19-4)
• EPA Substance Registry System: cyclohex-1-ene-1-methylamine(32917-19-4)

Safety Data

• Hazardous Substances Data: 32917-19-4(Hazardous Substances Data)

Usage

General Description

Cyclohex-1-ene-1-methylamine, also known as N-methylcyclohexylamine, is an organic compound with the chemical formula C7H13N. It is a colorless liquid with a fishy odor, and it is commonly used as a corrosion inhibitor and as a catalyst in chemical reactions. N-methylcyclohexylamine is also used in the production of pharmaceuticals, rubber chemicals, and agricultural products. It is considered to be a mild irritant to the skin and eyes, and prolonged exposure to high concentrations can cause respiratory irritation. Overall, N-methylcyclohexylamine plays a vital role in various industrial processes and applications.

InChI:InChI=1/C7H13N/c8-6-7-4-2-1-3-5-7/h4H,1-3,5-6,8H2

Upstream product

• 4845-04-9 1-cyclohexene-1-methanol 
• 81304-91-8 2-Cyclohex-1-enylmethyl-isoindole-1,3-dione 
• 5330-61-0 1-nitromethyl-cyclohexene 
• 108-94-1 cyclohexanone 
• 1453-24-3 1-ethylcyclohexene 
• 13048-17-4 cyclohex-2-enecarbonitrile 
• 1855-63-6 cyclohex-1-enecarbonitrile 
• 22546-81-2 cyclohex-1-enecarboxamide 

Downstream Products

• 4845-04-9 1-cyclohexene-1-methanol 
• 4065-80-9 2-methylenecyclohexanol 
• 934667-61-5 2-(4-chloro-phenyl)-2-{cyclohex-1-enylmethyl-[(7-methoxy-2-oxo-2H-chromen-4-yl)-acetyl]-amino}-N-isopropyl-acetamide 
• 58714-92-4 1-(cyclohex-1-en-1-ylmethyl)-biguanide hydrochloride 
• 1007834-63-0 N-(cyclohex-1-enylmethyl)benzenamine 
• 57981-23-4 N-(cyclohex-1-en-1-ylmethyl)-4-methylbenzenesulfonamide 

Relevant articles and documents

Synthesis of 6-aza-bicyclo[3,2,1]octan-3-ones via vinylogous imide photochemistry: An approach to the synthesis of the hetisine alkaloids [4]

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Pd-Catalyzed Remote Site-Selective and Stereoselective C(Alkenyl)-H Alkenylation of Unactivated Cycloalkenes

A palladium-catalyzed alkenylation involving remote δ-position C(alkenyl)-H activation of cycloalkenes reacting with electron-deficient alkenes is described. This method features excellent site selectivity and stereoselectivity to efficiently afford only E-selective highly substituted 1,3-diene derivatives with extra-ligand-free and good functional group tolerance including estrone and free N-H tryptamine under weakly alkaline conditions. Mechanistic studies suggest that picolinamide as a bidentate directing group enables the formation of unique alkenyl palladacycle intermediates.

Domino Aryne Annulation via a Nucleophilic-Ene Process

1,2-Benzdiyne equivalents possess the unique property that they can react with two arynophiles through iteratively generated 1,2- and 2,3-aryne intermediates. Upon rational modification on the second leaving group of these aryne precursors, a domino aryne annulation approach was developed through a nucleophilic-ene reaction sequence. Various benzo-fused N-heterocyclic frameworks were achievable under transition metal-free conditions with a broad substrate scope.