5829-79-8

Usage

Uses

Used in Pharmaceutical Industry:
((E)-4-CHLORO-2-METHYL-BUT-2-ENE-1-SULFONYL)-BENZENE(COENZYME Q10 INTERMEDIATE) is used as a key intermediate in the synthesis of Coenzyme Q10 for its role in maintaining cellular energy production and supporting overall health.
Used in Antitumor Applications:
((E)-4-CHLORO-2-METHYL-BUT-2-ENE-1-SULFONYL)-BENZENE(COENZYME Q10 INTERMEDIATE) is used in the synthesis of cecloprotoberberine derivatives, which are known for their anti-tumor properties. These derivatives have potential applications in the development of new therapeutic agents for cancer treatment.

Upstream product

• 98-09-9 benzenesulfonyl chloride 
• 78-79-5 isoprene 
• 106-99-0 buta-1,3-diene 
• 62-53-3 aniline 
• 7227-91-0 3,3-dimethyl-1-phenyl-triazene 
• 297766-64-4 1,3-Diphenyltriazen 

Downstream Products

• 53588-15-1 Phenylsulfonyl-4-methyl-3-formyloxy-1-buten-1 
• 53588-13-9 Phenylsulfonyl-4-methyl-3-acetoxy-1-buten-2 
• 73875-21-5 (2'E)-1-(3'-methyl-4'-phenylsulfonylbut-2'-enyl)-6-methyl-2,3,4,5-tetramethoxybenzene 
• 53588-16-2 (E)-4-hydroxy-2-methyl-1-phenylsulfonyl-2-butene 
• 73875-18-0 (2′E)-2-(3′-methyl-4′-phenylsulfonylbut-2′-enyl)-1,4-dimethoxy-3-methylnaphthalene 
• 26157-20-0 2-methyl-1-(phenylsulfonyl)-1,3-butadiene 

Relevant academic research and scientific papers

Diazo reactions with unsaturated compounds: VIII. Reaction of 1,3-butadiene and isoprene with aromatic and aliphatic-aromatic triazenes in the presence of sulfur(IV) oxide

1,3-Butadiene and 2-methyl-1,3-butadiene react with 1,3-diphenyltriazene, 1,3-di-p-tolyltriazene, and 1-aryl-3,3-dimethyl-1-triazenes in a sulfur(IV) oxide-saturated water-acetic acid-acetone solution containing NaCl or hydrochloric acid, and catalytic am

The Friedel-Crafts allylation of a prenyl group stabilized by a sulfone moiety: Expeditious syntheses of ubiquinones and menaquinones

An efficient synthetic method for the protected p-hydroquinone compounds 4 containing the C5 trans allylic sulfone moiety has been developed by the direct Friedel-Crafts allylation of the protected dihydroquinone 2 with 4-chloro-2-methyl-1-phenylsulfonyl-2-butene (7a) or 4-hydroxy-2-methyl-1-phenylsulfonyl-2-butene (7b). Expeditious total syntheses of coenzyme Q-10 and vitamin K2(20) have been demonstrated from these valuable key compounds 4a and 4b.