5840-41-5

Basic information

• Product Name: 1-Benzyl-3-nitrobenzene
• Synonyms: 1-Benzyl-3-nitrobenzene;1-Nitro-3-(phenylmethyl)benzene;1-Nitro-3-benzylbenzene;Phenyl(3-nitrophenyl)methane
• CAS NO: 5840-41-5
• Molecular Formula: C₁₃H₁₁NO₂
• Molecular Weight: 213.23
• Mol File: 5840-41-5.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 114-117 °C(Press: 0.04 Torr)
• Appearance: /
• Density: 1.180±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-Benzyl-3-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Benzyl-3-nitrobenzene(5840-41-5)
• EPA Substance Registry System: 1-Benzyl-3-nitrobenzene(5840-41-5)

Safety Data

• Hazardous Substances Data: 5840-41-5(Hazardous Substances Data)

Usage

Nitroaromatic compound

A type of aromatic compound containing a nitro group (-NO2) attached to a benzene ring.

Benzene ring

A six-carbon ring structure with alternating single and double bonds, forming the backbone of many organic compounds.

Nitro group

A functional group consisting of an oxygen atom double-bonded to a nitrogen atom (-NO2), which is known for its high electronegativity and reactivity.

Benzyl group

A functional group derived from a benzene ring with a single carbon-carbon bond to an alkyl chain, in this case, a single carbon (methyl) group.

Organic synthesis

A chemical process used to create new organic compounds by combining simpler molecules.

Intermediate

A temporary compound formed during a multi-step chemical reaction, which is used to produce the final product.

Pharmaceuticals

Medications or drugs used in the treatment, cure, prevention, or diagnosis of diseases.

Dyes

Chemical substances used to color fabrics, materials, or other substances.

Pesticides

Chemicals used to control, repel, or kill pests, including insects, weeds, and fungi.

Pale yellow solid

A physical description of the compound's appearance, indicating a pale yellow color and solid state at room temperature.

Insoluble in water

The compound does not dissolve in water, making it immiscible with aqueous solutions.

Soluble in organic solvents

The compound dissolves easily in organic solvents, such as alcohols, ethers, and hydrocarbons.

Safety precautions

Necessary measures taken to minimize the risk of accidents, exposure, or harm when handling and storing hazardous materials, such as 1-Benzyl-3-nitrobenzene.

Upstream product

• 3958-57-4 1-bromomethyl-3-nitrobenzene 
• 71-43-2 benzene 
• 7664-93-9 sulfuric acid 
• 619-25-0 3-Nitrobenzyl alcohol 
• 13331-27-6 m-nitrobenzene boronic acid 
• 100-44-7 benzyl chloride 
• 960-16-7 tributylphenylstannane 
• 2996-92-1 phenyl trimethylsiloxane 
• 372111-37-0 O,O-diethyl-m-nitrobenzyl phosphate 
• 98-80-6 phenylboronic acid 
• 55095-33-5 (3-nitrophenyl)phenylmethanol 
• 619-23-8 3-Nitrobenzyl chloride 
• 100-51-6 benzyl alcohol 
• 100-39-0 benzyl bromide 

Downstream Products

• 61424-26-8 3-benzylaniline 
• 1058345-46-2 2,2,2-trichloroethyl 3-nitrobenzhydrylcarbamate 
• 63021-27-2 acetic acid-(3-benzyl-anilide) 
• 2243-80-3 3-nitrobenzophenone 
• 3002-33-3 4-(3'-nitrobenzyl)-nitrobenzene 

Relevant articles and documents

Synthetic method of diarylmethanes

The invention discloses a synthetic method of diarylmethanes. The method is characterized in that benzyl pseudohalide and aromatic boric acid are reacted in an organic solvent under alkaline condition. The method employs easily available raw materials, conversion is realized under effect of no transition metal catalysis, water-free and oxygen-free are not required, Lewis acid catalysis is not required, the method has wide substrate universality, and various substituted diarylmethanes can be synthesized by the method.

Synthesis of diarylmethanes through palladium-catalyzed coupling of benzylic phosphates with arylsilanes

An efficient approach to the benzylation of arenes has been developed. The reactions described provide straightforward access to diarylmethanes through Pd-catalyzed coupling of benzylic phosphates with arylsilanes in good to excellent yields. The reaction tolerates a wide range of functionalities such as halide, alkoxyl, and nitro groups.

N-tosyloxycarbamates as reagents in rhodium-catalyzed C-H amination reactions

Metal nitrenes for use in C-H insertion reactions were obtained from N-tosyloxycarbamates in the presence of an inorganic base and a rhodium(II) dimer complex catalyst. The C-H amination reaction proceeds smoothly, and the potassium tosylate that forms as a byproduct is easily removed by filtration or an aqueous workup. This new methodology allows the amination of ethereal, benzylic, tertiary, secondary, and even primary C-H bonds. The intramolecular reaction provides an interesting route to various substituted oxazolidinones, whereas the intermolecular reaction gives trichloroethoxycarbonyl-protected amines that can be isolated with moderate to excellent yields and that cleave easily to produce the corresponding free amine. The development, scope, and limitations of the reactions are discussed herein. Isotopic effects and the electronic nature of the transition state are used to discuss the mechanism of the reaction.