58468-95-4

Upstream product

• 63996-47-4 2-hydroxy-2-methyl-3-phenylthiobutane 
• 108-98-5 thiophenol 
• 513-35-9 2-methyl-but-2-ene 
• 35875-02-6 2-methyl-2-phenylsulfanylbutan-3-one 
• 931-59-9 benzenesulfenyl chloride 
• 702-00-1 (2-methylallyl)(phenyl)sulfane 
• 74-88-4 methyl iodide 
• 58468-92-1 (2RS)-3-methyl-3-phenylsulfanylbutan-2-ol 

Downstream Products

• 58468-96-5 (1-Isopropenyl-1-methyl-pentylsulfanyl)-benzene 
• 62292-09-5 2-Methyl-3-phenylsulfinyl-1-buten 
• 63996-57-6 2,3,4-Trimethyl-3-(phenylthio)-pent-4-en-2-ol 

Relevant academic research and scientific papers

Selective Condensation of titanium Reagent with Carbonyl Compounds

titanium reagent generated easily from allyl ethyl sulfides condensed with aldehydes to give erythro-β-hydroxy sulfides in highly regio- and stereoselective manner.In contrast, crotyl ethyl sulfide reacted with aldehydes affording δ-hydroxy vinyl sulfide exclusively.The substitution pattern of the starting sulfide can have a pronounced effect on the selectivity in this condensation reaction, erythro-β-Hydroxy sulfide obtained was transfromed stereoselectively to the trans-vinyloxirane or 1,3-alkadiene.

FACILE FUNCTIONALIZATION OF THE ISOPROPYLIDENE TERMINUS OF ACYCLIC MONOTERPENES BY WAY OF BENZENESULFENYL CHLORIDE ADDITION

Highly site- and regioselective terminal functionalizations of acyclic monoterpenes 1 via benzenesulfenyl chloride addition followed by hydrolysis assisted by silica gel, dehydrochlorination under neutral or weakly basic condition, or dehydrochlorination by strongly basic treatment respectively providing β-hydroxy sulfides 3, terminal methallylic sulfides 4, or vinylsulfides 5 are developed.Conversion of 4 to terminal trans-allylic alcohols 10 via sulfoxides 9 by the Evans procedure is also described.