5848-60-2

Basic information

• Product Name: Benzene, [[(2E)-3-phenyl-2-propenyl]thio]-
• CAS NO: 5848-60-2
• Molecular Formula: C15H14S
• Molecular Weight: 226.342
• Mol File: 5848-60-2.mol
• Article Data: 44

Chemical Properties

• CAS DataBase Reference: Benzene, [[(2E)-3-phenyl-2-propenyl]thio]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, [[(2E)-3-phenyl-2-propenyl]thio]-(5848-60-2)
• EPA Substance Registry System: Benzene, [[(2E)-3-phenyl-2-propenyl]thio]-(5848-60-2)

Safety Data

• Hazardous Substances Data: 5848-60-2(Hazardous Substances Data)

Usage

General Description

Benzene, [(2E)-3-phenyl-2-propenyl]thio- is a chemical compound that consists of a benzene ring with a thioether functional group attached to it. It is also known as (E)-1-phenyl-2-(phenylthio)prop-1-ene. Benzene, [[(2E)-3-phenyl-2-propenyl]thio]- is generally used as a starting material and intermediate in organic synthesis. It can be used in the production of a variety of organic chemicals and pharmaceuticals. It is important to handle this compound with caution as benzene derivatives can be toxic and potentially harmful if not handled properly.

Upstream product

• 18740-08-4 3-phenyl-3-(phenylthio)prop-1-ene 
• 13702-03-9 phenyl (3-phenylprop-2-yn-1-yl) sulfide 
• 882-33-7 diphenyldisulfane 
• 4393-06-0 1-Phenyl-2-propen-1-ol 
• 108-98-5 thiophenol 
• 444575-79-5 carbonic acid 1,1-dimethylethyl 1-phenyl-2-propenyl ester 
• 930-69-8 sodium thiophenolate 
• 87802-71-9 (E)-methyl cinnamyl carbonate 
• 4392-24-9 Cinnamyl bromide 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 
• 21087-29-6 trans-3-phenylprop-2-enyl chloride 
• 4392-24-9 3-bromo-1-phenyl-1-propenyl bromide 
• 52372-79-9 trans-Zimtaldehydhydrazon 
• 2327-99-3 1-phenylpropadiene 

Downstream Products

• 16212-07-0 trans-cinnamyl phenyl sulfone 
• 102680-02-4 (E)-1-phenyl-3-phenylsulfinylprop-1-ene 
• 112157-73-0 2-((E)-3-Phenyl-allyloxy)-cyclopent-1-enecarboxylic acid ethyl ester 
• 191406-50-5 (2R,3S)-tert-butyl 3-phenyl-2-phenylthio-4-pentenoate 
• 191406-52-7 (2R,3S)-3-Phenyl-2-phenylsulfanyl-pent-4-enoic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 110332-81-5 benzenesulfenyl-(1-phenyl-allyl)-(toluene-4-sulfonyl)-amine 
• 2973-86-6 lithium thiophenoxide 
• 54962-99-1 cinnamyllithium 
• 14371-10-9 (E)-3-phenylpropenal 
• 100-52-7 benzaldehyde 
• 882-33-7 diphenyldisulfane 

Relevant articles and documents

Gold-catalyzed thioetherification of allyl, benzyl, and propargyl phosphates

Gold-catalyzed thioetherification of C(sp3)-O bonds is described. The reaction of allyl phosphates and thiosilanes in the presence of gold nanoparticles supported on ZrO2 proceeded efficiently under mild reaction conditions to give the corresponding allyl sulfides in excellent yields. ZrO2-Supported gold nanoparticles showed excellent catalytic turnover and reusability. In addition, the C-O bonds of benzyl and propargyl phosphates underwent thioetherification to afford benzyl and propargyl sulfides. The reaction of an optically active benzyl phosphate proceeded with excellent chirality transfer to give a benzyl sulfide with high enantiomeric purity. Control experiments corroborated that soluble gold species were responsible for the efficient thioetherification of C-O bonds of phosphates, and characterization of the catalysts revealed that cationic gold species at the surface of gold nanoparticles supported on ZrO2 served as a source for highly active catalytic species.

Hemin Catalyzed Dealkylative Intercepted [2, 3]-Sigmatropic Rearrangement Reactions of Sulfonium Ylides with 2, 2, 2-Trifluorodiazoethane

A dealkylative intercepted [2, 3]-sigmatropic rearrangement reaction of allylic sulfides with 2, 2, 2-trifluorodiazoethane (CF3CHN2) is reported, the commercially available and biocompatible catalyst hemin was found to efficiently catalyze this transformation across a diverse set of allylic sulfides with in situ generated CF3CHN2, providing excellent yields (up to 99%) under mild condition without inert gas protection. In addition, CF3CHN2 exhibited unique reactivity toward this process compared with other frequently used diazo reagents. This work expands the range of carbene-mediated transformations catalyzed by hemin and introduces a concise and general strategy for exploiting new possibility of reactions concerning organosulfides. (Figure presented.).

Nanolayered cobalt-molybdenum sulphides (Co-Mo-S) catalyse borrowing hydrogen C-S bond formation reactions of thiols or H2S with alcohols

Nanolayered cobalt-molybdenum sulphide (Co-Mo-S) materials have been established as excellent catalysts for C-S bond construction. These catalysts allow for the preparation of a broad range of thioethers in good to excellent yields from structurally diverse thiols and readily available primary as well as secondary alcohols. Chemoselectivity in the presence of sensitive groups such as double bonds, nitriles, carboxylic esters and halogens has been demonstrated. It is also shown that the reaction takes place through a hydrogen-autotransfer (borrowing hydrogen) mechanism that involves Co-Mo-S-mediated dehydrogenation and hydrogenation reactions. A novel catalytic protocol based on the thioetherification of alcohols with hydrogen sulphide (H2S) to furnish symmetrical thioethers has also been developed using these earth-abundant metal-based sulphide catalysts.