586-10-7

Usage

Uses

Used in Dye and Pigment Industry:
3-Methoxy-5-nitroaniline is used as a chemical intermediate for the synthesis of various dyes and pigments. Its unique chemical structure contributes to the color and stability of these products, making it a valuable component in this industry.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 3-Methoxy-5-nitroaniline is utilized as an intermediate in the production of various medications. Its chemical properties allow it to be a key component in the synthesis of active pharmaceutical ingredients, contributing to the development of new and effective drugs.
Used as a Chemical Reagent in Organic Synthesis:
3-Methoxy-5-nitroaniline also serves as a chemical reagent in organic synthesis processes. Its reactivity and functional groups make it suitable for use in a variety of chemical reactions, facilitating the formation of desired products in research and industrial applications.
Safety Precautions:
Given its toxic nature, 3-Methoxy-5-nitroaniline requires proper handling and storage to prevent ingestion, inhalation, or skin and eye contact. Safety measures such as wearing protective gear, using containment systems, and adhering to material safety data sheets should be strictly followed to ensure the well-being of individuals working with 3-METHOXY-5-NITROANILINE.

InChI:InChI=1/C7H8N2O3/c1-12-7-3-5(8)2-6(4-7)9(10)11/h2-4H,8H2,1H3

Upstream product

• 5327-44-6 3,5-dinitroanisole 
• 7783-06-4 hydrogen sulfide 
• 67-56-1 methanol 
• 99-35-4 1,3,5-trinitrobenzene 
• 292635-40-6 3-methoxy-5-nitrobenzamide 
• 5350-56-1 4-amino-1-methoxy-3,5-dinitrobenzene 
• 78238-13-8 3-methoxy-5-nitrobenzoic acid methyl ester 
• 78238-12-7 3-methoxy-5-nitrobenzoic acid 
• 116496-83-4 acetic acid-(3-methoxy-5-nitro-anilide) 

Downstream Products

• 117162-84-2 3-methoxy-5-nitro-phenyl isocyanate 
• 16618-67-0 3-bromo-5-nitroanisole 
• 7145-49-5 3-methoxy-5-nitrophenol 
• 55910-07-1 1-chloro-3-methoxy-5-nitrobenzene 
• 861792-70-3 2-bromo-3-methoxy-5-nitro-aniline 
• 861792-66-7 2,4,6-tribromo-3-methoxy-5-nitro-aniline 
• 116496-83-4 acetic acid-(3-methoxy-5-nitro-anilide) 
• 380635-83-6 sulfanilic acid-(3-methoxy-5-nitro-anilide) 
• 24920-72-7 5.5'-Dinitro-3.3'-dimethoxy-azobenzol 
• 79990-25-3 1-iodo-3-methoxy-5-nitro-benzene 
• 62606-05-7 (3-Methoxy-5-nitro-phenyl)-(2,4,6-trinitro-phenyl)-amine 
• 350800-67-8 N-(3-methoxy-5-nitro-phenyl)-dimethyl-amine 
• 907181-01-5 2,3-dichloro-6-(3-methoxy-5-nitro-phenyl)-pyrrolo[3,4-b]pyrazine-5,7-dione 
• 952482-01-8 N-(3-Methoxy-5-nitrophenyl)-methansulfonamide 

Relevant academic research and scientific papers

Discovery of novel and potent leukotriene B4 receptor antagonists. Part 1

The inhibition of LTB4 binding to and activation of G-protein-coupled receptors BLT1 and BLT2 is the premise of a treatment for several inflammatory diseases. In a lead optimization effort starting with the leukotriene B4 (LTB4

Leukotriene B4 Inhibitors

Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, COPD

Coupling compounds and hair dyeing compositions containg them

The present invention refers to Compound of the formula (I) wherein X is oxygen or sulphur; R1 is (C1-C4)-alkyl, (C1-C4)-alkyl which is substituted by hydroxy, (C1-C4)-alkoxy, hy

Allosteric regulation of the conformational dynamics of a cavitand receptor

Inspired by allostery in nature, we synthesized cavitand 1 and investigated regulation of its conformational dynamics. Quantitative 1H NMR studies have revealed that the rate of the conformational isomerization of 1 can be modulated using the e

Substituted benzamide inhibitors of rhinovirus 3C protease

Nonpeptide benzamide-containing inhibitors of human rhinovirus (HRV) 3C protease are described.

Substituted benzamide inhibitors of human rhinovirus 3C protease: Structure-based design, synthesis, and biological evaluation

A series of nonpeptide benzamide-containing inhibitors of human rhinovirus (HRV) 3C protease was identified using structure-based design. The design, synthesis, and biological evaluation of these inhibitors are reported. A Michael acceptor was combined with a benzamide core mimicking the P1 recognition element of the natural 3CP substrate, α,β-Unsaturated cinnamate esters irreversibly inhibited the 3CP and displayed antiviral activity (EC50 0.60/μM, HRV-16 infected H1-HeLa cells). On the basis of cocrystal structure information, a library of substituted benzamide derivatives was prepared using parallel synthesis on solid support. A 1.9 A? cocrystal structure of a benzamide inhibitor in complex with the 3CP revealed a binding mode similar to that initially modeled wherein covalent attachment of the nucleophilic cysteine residue is observed. Unsaturated ketones displayed potent reversible inhibition but were inactive in the cellular antiviral assay and were found to react with nucleophilic thiols such as DTT.

Synthesis of Unlabelled and Carboxyl-Labelled 3-Amino-5-hydroxybenzoic Acid

Efficient syntheses are reported of the natural amino acid 3-amino-5-hydroxybenzoic acid in unlabelled and carboxyl-labelled forms from 3,5-dinitrobenzoic acid and 3,5-dinitroanisole, respectively.