5350-56-1

Basic information

• Product Name: p-Anisidine, 2,6-dinitro-,
• Synonyms: p-Anisidine, 2,6-dinitro-,
• CAS NO: 5350-56-1
• Molecular Formula: C₇H₇N₃O₅
• Molecular Weight: 213.15
• Mol File: 5350-56-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 414.7°Cat760mmHg
• Flash Point: 204.6°C
• Appearance: /
• Density: 1.529g/cm³
• Vapor Pressure: 4.38E-07mmHg at 25°C
• Refractive Index: 1.64
• CAS DataBase Reference: p-Anisidine, 2,6-dinitro-,(CAS DataBase Reference)
• NIST Chemistry Reference: p-Anisidine, 2,6-dinitro-,(5350-56-1)
• EPA Substance Registry System: p-Anisidine, 2,6-dinitro-,(5350-56-1)

Safety Data

• Hazardous Substances Data: 5350-56-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H7N3O5/c1-15-4-2-5(9(11)12)7(8)6(3-4)10(13)14/h2-3H,8H2,1H3

Upstream product

• 7664-93-9 sulfuric acid 
• 1071708-53-6 (4-methoxy-2,6-dinitro-phenyl)-carbamic acid ethyl ester 
• 123-91-1 1,4-dioxane 
• 672288-48-1 2-benzenesulfonyl-5-methoxy-1,3-dinitro-benzene 
• 7664-41-7 ammonia 
• 7403-13-6 acetic acid-(4-hydroxy-2.6-dinitro-anilide) 
• 64172-26-5 N-Butyl-N-methyl-2,6-dinitro-p-anisidin 
• 64172-27-6 N-Butyl-N-methyl-2-nitro-p-anisidin 
• 119-81-3 4-methoxy-2-nitroacetanilide 
• 5327-44-6 3,5-dinitroanisole 
• 61511-69-1 N-ethyl-4-methoxy-2,6-dinitro-aniline 
• 861529-91-1 3-nitro-benzenesulfonic acid-(4-methoxy-2,6-dinitro-anilide) 
• 1150-26-1 N-(4-Methoxy-phenyl)-4-methyl-benzenesulfonamide 
• 4284-48-4 N-(4-methoxyphenyl)methanesulfonamide 

Downstream Products

• 502182-42-5 (4-chloro-2-nitro-phenyl)-(4-methoxy-2,6-dinitro-phenyl)-amine 
• 10265-97-1 4-chloro-3,5-dinitro-anisole 
• 76179-57-2 5-methoxy-3-nitrobenzene-1,2-diamine 
• 4435-68-1 5-methoxy-benzene-1,2,3-triyltriamine 
• 89677-78-1 3,5-dinitro-4-iodoanisole 
• 5327-44-6 3,5-dinitroanisole 
• 7145-49-5 3-methoxy-5-nitrophenol 
• 586-10-7 3-methoxy-5-nitroaniline 
• 90559-67-4 4-methoxy-N,N-dimethyl-2,6-dinitro-aniline 
• 64172-25-4 N-methyl-4-methoxy-2,6-dinitroaniline 
• 7403-15-8 N-(7-methoxy-quinoxalin-5-yl)-acetamide 
• 7403-14-7 7-methoxy-quinoxalin-5-ylamine 
• 101257-95-8 6-methoxy-1(3)H-benzimidazol-4-ylamine 
• 854634-08-5 N-(6-methoxy-1⁽³⁾H-benzimidazol-4-yl)-toluene-4-sulfonamide 

Relevant articles and documents

Direct amination of 1-substituted 3,5-dinitrobenzenes by 1,1,1-trimethylhydrazinium iodide

The amination of 1-X-3,5-dinitrobenzenes via the vicarious nucleophilic substitution of hydrogen (VNS) with 1,1,1-trimethylhydrazinium iodide (TMHI) in the presence of t-BuOK or NaOMe in DMSO was studied. It was observed (when X = OMe, OCH2CF3, OCH2CF2CF2H, OPh) that the amination occurs regioselectively (ratio of ortho/para-isomers is ～9:1) and with high yield. For X = SPh or SCH2Ph, the reaction proceeded with a low yield (less than 20%), with a ratio of ortho/para-isomers ≈1:1. For X = PhSO2 and 2 equiv of TMHI, a double amination occurs and 2,4-diamino-3,5- dinitro-1-phenylsulfonylbenzene predominates in the mixture of isomers. Under the same conditions, 1,3,5-trinitrobenzene undergoes a double amination to yield 2,4-diamino-1,3,5-trinitrobenzene. A proposed mechanism for this reaction is discussed.

Oxidation of Aryldialkylamines with Cerium(IV) Ammonium Nitrate and Thallium(III) Nitrate

Nine alkylmethylanilines were oxidised with cerium(IV)ammonium nitrate and thallium(III) nitrate in acetic acid, acetonitrile, and methanol.Reaction products were those deriving from demethylation, dealkylation, and aromatic nitration at positions ortho and para to the amino-group.The ratio between demethylation and dealkylation and between them and aromatic nitration is discussed in terms of (i) the oxidising power and electrophilicity of the reagent and (ii) the co-ordinative properties of the solvent.