58632-83-0

Basic information

• Product Name: 2-propylacetophenone
• Synonyms: 2-propylacetophenone;Ethanone, 1-(2-propylphenyl)- (9CI)
• CAS NO: 58632-83-0
• Molecular Formula: C₁₁H₁₄O
• Molecular Weight: 162.22826
• Product Categories: ACETYLGROUP
• Mol File: 58632-83-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-propylacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-propylacetophenone(58632-83-0)
• EPA Substance Registry System: 2-propylacetophenone(58632-83-0)

Safety Data

• Hazardous Substances Data: 58632-83-0(Hazardous Substances Data)

Upstream product

• 63620-04-2 2-propyl-benzoyl chloride 
• 506-82-1 dimethylcadmium 
• 2743-00-2 (E)-4-methoxy-N-(1-phenylethylidene)benzenamine 
• 75-26-3 isopropyl bromide 
• 1941-30-6 tetra-n-propylammonium bromide 
• 98-86-2 acetophenone 
• 64664-07-9 1-(2-allylphenyl)ethan-1-one 

Downstream Products

• 16021-20-8 1-ethyl-2-propyl-benzene 
• 1310684-57-1 C₂₁H₂₄N₄O 

Relevant articles and documents

Iridium-Catalyzed Alkene-Selective Transfer Hydrogenation with 1,4-Dioxane as Hydrogen Donor

The iridium-catalyzed transfer hydrogenation of alkenes using 1,4-dioxane as a hydrogen donor is described. The use of 1,2-bis(dicyclohexylphosphino)ethane (DCyPE), featuring bulky and highly electron-donating properties, led to high catalytic activity. A polystyrene-cross-linking bisphosphine PS-DPPBz produced a reusable heterogeneous catalyst. These homogeneous and heterogeneous protocols achieved chemoselective transfer hydrogenation of alkenes over other potentially reducible functional groups such as carbonyl, nitro, cyano, and imino groups in the same molecule.

Investigations of the generality of quaternary ammonium salts as alkylating agents in direct C-H alkylation reactions: Solid alternatives for gaseous olefins

C-H alkylation reactions using short chain olefins as alkylating agents could be operationally simplified on the lab scale by using quaternary ammonium salts as precursors for these gaseous reagents: Hofmann elimination delivers in situ the desired alkenes with the advantage that the alkene concentration in the liquid phase is high. In case a catalytic system did not tolerate the conditions for Hofmann elimination, a very simple spatial separation of both reactions, Hofmann elimination and direct alkylation, was achieved to circumvent possible side reactions or catalyst deactivation. Additionally, the truly catalytically active species of a rhodium(i) mediated alkylation reaction could be identified by using this approach.

Cobalt-catalyzed ortho alkylation of aromatic imines with primary and secondary alkyl halides

We report here cobalt-N-heterocyclic carbene catalytic systems for the ortho alkylation of aromatic imines with alkyl chlorides and bromides, which allows the introduction of a variety of primary and secondary alkyl groups at room temperature. The stereochemical outcomes of the reaction of secondary alkyl halides suggest that the present reaction involves single-electron transfer from a cobalt species to the alkyl halide to generate the corresponding alkyl radical. A cycloalkylated product obtained by this method can be transformed into unique spirocycles through manipulation of the directing and cycloalkyl groups.