58742-64-6

Usage

InChI:InChI=1/C6H12O5S/c1-4-10-6(7)5(2)11-12(3,8)9/h5H,4H2,1-3H3

Upstream product

• 97-64-3 ethyl 2-hydroxypropionate 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 55602-05-6 α-thiocyanato-propionic acid ethyl ester 
• 39574-16-8 2-isothiocyanatopropionic acid ethyl ester 
• 58742-81-7 5-methyl-1,2-oxathiolane-4-one 2,2-dioxide 
• 349-43-9 ethyl 2-fluoropropionate 
• 96928-09-5 ethyl 2-(4-acetylphenoxy)-propanoate 
• 51264-73-4 Ethyl-2-(4-formylphenoxy)propionat 
• 63650-08-8 (+)-ethyl 2-(4-benzyloxyphenoxy)propionate 
• 51338-06-8 D-(+)-2-[4-(2,4-dichlorophenoxy)-phenoxy]-propionic acid ethyl ester 
• 64165-28-2 D-(+)-2-[4-(4-bromo-2-chloro-phenoxy)-phenoxy]-propionic acid ethyl ester 
• 51337-67-8 D-(+)-2-[4-(4-chlorophenoxy)-phenoxy]propionic acid ethyl ester 
• 124342-60-5 cis-tetracarbonyl(2-ethoxy-1-methyl-2-oxoethyl)(triphenylphosphine)rhenium 
• 124378-94-5 trans-tetracarbonyl(2-ethoxy-1-methyl-2-oxoethyl)(triphenylphosphine)rhenium 
• 41283-72-1 ibuprofen ethyl ester 
• 875148-65-5 CpMo(CO)3(CH(CH₃)COOC₂H₅) 

Relevant academic research and scientific papers

Cyclopentadienyl molybdenum alkyl ester complexes as catalyst precursors for olefin epoxidation

New molybdenum complexes of the type [CpMo(CO)3X] containing ligands of the formula X = CHR2CO(OR1) where R1 = ethyl (1), menthyl (4), and bornyl (5) and R2 = H; R1 = ethyl and R2 = methyl (2) and phenyl (3) have been synthesized and characterized by NMR and IR spectroscopy and X-ray crystallography. These compounds have been applied as catalyst precursors for achiral and chiral epoxidation of unfunctionalized olefins with tert-butyl hydroperoxide (TBHP) as the oxidant at 22 °C (in CH2Cl2) and 55°C (in CHCl3). The substrates cis-cyclooctene, 1-octene, cis- and trans-stilbene, and trans-β-methylstyrene were selectively and quantitatively converted into their epoxides using a catalyst:substrate:oxidant ratio of 1:100:200 within 4 h at room temperature in CH2Cl2 and within 15 min at 55°C in CHCl3. Complexes 1-5 are precursors of active epoxidation catalysts and turnover frequencies (TOFs) of ca. 1200 h-1 are obtained with cis-cyclooctene as the substrate. No enantioselectivity is observed with trans-β-methylstyrene as the substrate despite the application of enantiomerically pure precatalysts. In situ monitoring of catalytic epoxidation of cis-cyclooctene with complex 5 by 1H and 13C NMR spectroscopy suggests that the chiral alkyl ester side chain is retained during oxidation with TBHP. During epoxidation, the primary catalytic species is the dioxo complex [CpMoO2X]. After near complete conversion of cis-cyclooctene to its epoxide, further oxidation of the dioxo complex to oxo-peroxo complex [CpMo(η2-O2)(O)X] takes place. The oxo-peroxo complex is also an active epoxidation catalyst.

Synthesis and Pharmacological Evaluation of New Chemical Entities from Ibuprofen as Novel Analgesic Candidates

Non-steroidal anti-inflammatory drugs (NSAIDs) are the first choice of drugs that are normally used for the treatment of pain and inflammation. Ibuprofen (I) and its analogues as the most widely used NSAIDs have been synthesized in recent years. In an effort to establish new candidates with improved analgesic properties, derivatives (II-VII) with substituted aromatic as well as aliphatic moieties were synthesized in this experiment and evaluated in formalin test with rats. The results were compared to ibuprofen and control groups. Findings indicated that derivatives with new alkylphenyl rings (VI and VII) had some similar or more analgesic activities relative to the control and ibuprofen groups, respectively; which could be justified as to more alkyl and phenyl groups instead of p-isobutylphenyl moiety in I.

Scavenger assisted combinatorial process for preparing libraries of tertiary amine compounds

This invention relates to a novel solution phase process for the preparation of tertiary amine combinatorial libraries. These libraries have utility for drug discovery and are used to form wellplate components of novel assay kits.

Process for the preparation of D(+)-2-(4-acetylphenoxy)-propionic esters

Process for the preparation of D(+)-2-(4-acetylphenoxy)-propionic esters Preparation of D(+)-2-(4-acetylphenoxy)-propionic esters of the formula STR1 by reacting 4-hydroxyacetophenone with L-halo- or sulfonyloxy-lactic esters in a basic medium at temperatures ≤50° C.

Optically active 1-aromatic-group-substituted-1-alkanones and methods for their manufacture

A manufacturing method is described for the preparation of optically active 1-aromatic-group-substituted-1-alkanones characterized in that an optically active alkane acid halide is allowed to react with an aromatic compound in the presence of a Lewis acid. The optically active 1-aromatic-group-substituted-1-alkanones are useful intermediates in the preparation of optically active alpha-arylalkanoic acids, which are useful as pharmaceutical, e.g. anti-inflammatory, analgesic and anti-pyretic, agents and as insecticidal agents.