58751-08-9

Basic information

• Product Name: 2,3,4,5,6-pentafluoroformanilide
• Synonyms: 2,3,4,5,6-pentafluoroformanilide
• CAS NO: 58751-08-9
• Molecular Weight: 211.091
• Mol File: 58751-08-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,3,4,5,6-pentafluoroformanilide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4,5,6-pentafluoroformanilide(58751-08-9)
• EPA Substance Registry System: 2,3,4,5,6-pentafluoroformanilide(58751-08-9)

Safety Data

• Hazardous Substances Data: 58751-08-9(Hazardous Substances Data)

Upstream product

• 771-60-8 2,3,4,5,6-pentafluoroaniline 
• 7646-69-7 sodium hydride 
• 109-94-4 formic acid ethyl ester 
• 1801-15-6 2-(2,3,4,5,6-pentafluoro-anilino)-ethanol 
• 30807-79-5 C₆HBCl₂F₅N 
• 68-12-2 N,N-dimethyl-formamide 
• 64-18-6 formic acid 
• 143896-70-2 N-(2,3,4,5,6-pentafluorophenyl)-1-phenylmethanimine 

Downstream Products

• 945041-53-2 N-formyl-N,N'-decafluorodiphenyl-tetrafluoro-1,4-phenylene-diamine 
• 945041-51-0 N,N'-decafluorodiphenyl-tetrafluoro-1,4-phenylenediamine 
• 945041-54-3 N-formyl-4,4'-bis[(pentafluorophenyl)amino]-2,2',3,3',5,5',6,6'-octafluorodiphenylamine 
• 1535-92-8 2,2',3,3',4,4',5,5',6,6'-decafluorodiphenylamine 
• 21132-29-6 methyl (perfluorophenyl)carbamate 
• 1591-95-3 pentafluorophenyl isocyanate 
• 58751-09-0 2,3,4,5,6-pentafluorophenyl isocyanide 
• 68090-77-7 N,N′-bis(pentafluorophenyl)methanimidamine 
• 64317-34-6 N-(pentafluorophenyl)carbonimidoyl dichloride 

Relevant articles and documents

[18F]/19F exchange in fluorine containing compounds for potential use in 18F-labelling strategies

Exchange of [18F]fluoride with 19F in various organofluorine compounds in concentrations ranging from 0.06 to 56 mM was explored. We aimed to explore whether exchange reactions can be a potential useful labelling strategy, when there are no requirement of high specific radioactivity. Parameters such as solvents, temperature, conventional vs microwave heating, and the degree of fluorine load in some aromatic and alkyl compounds were investigated with regard to radiochemical yield and specific radioactivity. A series of fluorobenzophenones (1-6), 1-(4-fluorophenyl)ethanone (7), various activated and deactivated fluoro benzenes (8-16), N-(pentafluorophenyl)benzamide (17), (pentafluorophenyl)formamide (18), (tridecafluorohexyl)benzene (19) and tetradecafluorohexane (20) were subjected to [18F]/19F exchange. To test this strategy to label biologically active molecules containing fluorine atoms in an aryl group, two analogues of WAY-100635 (21-22), Lapatinib (23), 2,5,6,7,8-pentafluoro-3- methylnaphthoquinone (24) and 1-(2,4-difluorophenyl)-3-(4-fluorophenyl)-propan- 1-one (25) were investigated. The multi-fluorinated molecules containing an electron-withdrawing group were successfully labelled at room temperature, whereas the monofluorinated, as well as those containing an electron-donating group, required heating for the exchange reaction to take place. Copyright

Mechanisms of cage reactions: Kinetics of combination and diffusion after picosecond photolysis of iron(II) porphyrin ligated systems

The kinetics of transient absorption changes for a number of protoheme-ligand systems after subpicosecond photolysis have been investigated. When the photolyzed ligand is tert-butyl, pentachlorophenyl, pentafluorophenyl, 5α-cholestan-3α-yl, or 5α-cholesta