587884-71-7Relevant academic research and scientific papers
Rational Design, Synthesis and Evaluation of Oxazolo[4,5-c]-quinolinone Analogs as Novel Interleukin-33 Inhibitors
Byun, Youngjoo,Cho, Haelim,Ho Jeon, Young,Hoon Kim, Kyong,Jang, Geonhee,Kim, Yujin,Lee, Kiho,Lee, Taeyun,Ma, Chao,Paek, Jiwon,Park, Seonghu,Shin -, Yujin,Son, Sang-Hyun,Son, Seyoung,Woo Jung, Yong,Yong Lee, Ki
, p. 3702 - 3712 (2021/11/19)
Interleukin-33 (IL-33) is an epithelial-derived cytokine that plays an important role in immune-mediated diseases such as asthma, atopic dermatitis, and rheumatoid arthritis. Although IL-33 is considered a potential target for the treatment of allergy-rel
NOVEL QUINOLINONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ALLERGIC DISEASES SUCH AS ASTHMA OR ATOPIC DERMATITIS INCLUDING THE QUINOLINONE DERIVATIVE AS ACTIVE INGREDIENT
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Paragraph 0028; 0057-0059, (2020/05/29)
The present invention relates to anovel quinolinone derivative compound that regulates intracellular signal transduction mediated by TSLP and IL-33 to exhibit efficacy in preventing or treating allergic diseases such as asthma or atopic dermatitis. The qu
Synthesis of 2-aryl-oxazolo[4,5-c]quinoline-4(5H)-ones and 2-aryl-thiazolo[4,5-c]quinoline-4(5H)-ones
Hodgetts, Kevin J.,Kershaw, Mark T.
, p. 2911 - 2914 (2007/10/03)
(Matrix presented) Novel and highly efficient syntheses of oxazolo[4,5-c]quinoline-4(5H)-ones (1) and thiazolo[4,5-c]quinoline-4(5H)-ones (2) from ethyl 2-chlorooxazole-4-carboxylate (4) and ethyl 2-bromo-5-chlorothiazole-4-carboxylate (13), respectively,
