58814-37-2Relevant academic research and scientific papers
Expedient synthesis of functionalized triarylmethanols through tandem formation of geminal C-C and C-O bonds
Tian,Sui, Yi,Gu, Yonghong,Tian, Shi-Kai
supporting information, p. 3475 - 3479 (2013/02/22)
The rearrangement/oxidation of N,N-disubstituted anilines and the formal dehydrogenative cross-coupling of diarylmethanols with aniline derivatives have been developed for the preparation of symmetric and unsymmetric functionalized triarylmethanols. Both reactions proceed smoothly in trifluoroacetic acid in the presence of an inexpensive oxidant (manganese dioxide or potassium persulfate) and a catalytic amount of palladium diacetate to give a range of functionalized triarylmethanols in moderate to good yields and with extremely high regioselectivity. The two unprecedented reactions involve tandem formation of geminal C-C and C-O bonds, and they are synthetically useful, atom-efficient, and operationally simple.
Development of hydrophilic photolabile hydroxyl protecting groups
Yang, Haishen,Zhou, Lei,Wang, Pengfei
, p. 514 - 517 (2012/06/30)
Hydrophilic photolabile protecting groups (PPGs) for hydroxyl protection have been developed. The new PPGs are derived from 3-(dimethylamino)trityl (DMATr) by replacing the two methyl groups with two hydrophilic butyryl groups. The new PPG reagents can be readily prepared and installed. They are stable in the dark but can be removed cleanly and efficiently in aqueous environments upon irradiation with a UV lamp or sunlight.
The 'benzostabase' protecting group for primary amines; application to aromatic amines
Bonar-Law,Davis,Dorgan
, p. 6721 - 6724 (2007/10/02)
Anilines can be protected as 'benzostabase' (BSB) derivatives by dehydrogenative silylation with 1,2-bis(dimethylsilyl)benzene. The derivatives have useful acid stability and are stable to chromatography on silica gel. It is demonstrated that the BSB grou
