59163-72-3

Basic information

• Product Name: 2-(4-chlorophenyl)ethyl acetate
• CAS NO: 59163-72-3
• Molecular Formula: C₁₀H₁₁ClO₂
• Molecular Weight: 198.6461
• Mol File: 59163-72-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 266.8°C at 760 mmHg
• Flash Point: 124.4°C
• Density: 1.163g/cm³
• Vapor Pressure: 0.00846mmHg at 25°C
• Refractive Index: 1.518
• CAS DataBase Reference: 2-(4-chlorophenyl)ethyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chlorophenyl)ethyl acetate(59163-72-3)
• EPA Substance Registry System: 2-(4-chlorophenyl)ethyl acetate(59163-72-3)

Safety Data

• Hazardous Substances Data: 59163-72-3(Hazardous Substances Data)

Usage

Physical state

Clear, colorless liquid

Aroma

Sweet, floral

Uses

Fragrance ingredient in perfumes and personal care products; flavoring agent in baked goods and confections

Derivation

Acetic acid and 4-chlorophenyl-2-ethanol

Precautions

Can be irritating to skin, eyes, and respiratory system if not properly handled

Upstream product

• 108-24-7 acetic anhydride 
• 502699-22-1 2-[2-(4-chloro-phenyl)-ethoxy]-tetrahydro-pyran 
• 1875-88-3 2-(4-Chlorophenyl)ethanol 
• 1878-66-6 4-chlorophenylacetic Acid 
• 75-36-5 acetyl chloride 
• 6948-71-6 toluene-4-sulfonic acid 2-(4-chloro-phenyl)-ethyl ester 
• 64-19-7 acetic acid 
• 108-90-7 chlorobenzene 

Relevant articles and documents

ZrCl4 as a mild and efficient catalyst for the one-pot conversion of TBS and THP ethers to acetates

A mild, efficient and chemoselective method has been developed for the direct transformation of tert-butyldimethylsilyl and tetrahydropyranyl protected alcohols into the corresponding acetates with acetic anhydride and zirconium(IV) chloride as the catalyst in acetonitrile, in a one-pot reaction with high yields and short reaction times. This method has been applied to a variety of substrates.

A fast and practical approach to tetrahydropyranylation and depyranylation of alcohols using indium triflate

Indium triflate-mediated tetrahydropyranylation of alcohols in dichloromethane and depyranylation of these products in aqueous methanol utilizing the same reagent but different molar ratio is described. In addition, indium triflate-promoted conversion of tetrahydropyran ethers to their corresponding acetates has also been described.