59239-12-2Relevant academic research and scientific papers
Visible-light- And bromide-mediated photoredox Minisci alkylation of N-heteroarenes with ester acetates
Deng, Guo-Jun,Huang, Huawen,Shi, Hang,Wang, Chunlian
supporting information, p. 9177 - 9181 (2021/11/16)
A visible-light-induced photoredox Minisci alkylation reaction of N-heteroarenes with ethyl acetate has been reported. The low-toxic ethyl acetate was used for the first time as an alkylation reagent. Hence, 4-quinazolinones, quinolines and pyridines reacted smoothly in the current reaction system. Mechanistic studies indicate that LiBr plays a key role to dramatically improve the efficiency of the reaction by the mediation of hydrogen atom transfer. This journal is
Rare-earth-catalyzed C-H bond addition of pyridines to olefins
Guan, Bing-Tao,Hou, Zhaomin
supporting information; experimental part, p. 18086 - 18089 (2012/01/03)
An efficient and general protocol for the ortho-alkylation of pyridines via C-H addition to olefins has been developed, using cationic half-sandwich rare-earth catalysts, which provides an atom-economical method for the synthesis of alkylated pyridine der
Thermal characterization of the solid state and raw material fluconazole by thermal analysis and pyrolysis coupled to GC/MS
Moura, Elisana Afonso,Correia, Lidiane Pinto,Pinto, Marcia Ferraz,Procopio, Jose Valdilanio Virgulino,De Souza, Fabio Santos,MacEdo, Rui Oliveira
body text, p. 289 - 293 (2010/08/04)
This article had studied the thermal characterization of the raw material and different fluconazole crystals, obtained through recrystallization with different solvents using thermoanalytical techniques (TG, DTA, DSC-50, DSC Photovisual, DSC-60) and Pyr-GC/MS. The results confirmed that the fluconazole volatilizes without decomposition until 250 °C. Pyr-GC/MS showed hexachlorobenzene like impurities in fluconazole raw material.
REGIOSELECTIVE SYNTHESIS OF 2-SUBSTITUTED PYRIDINES VIA GRIGNARD ADDITION TO 1-(ALKOXYCARBOXY)-PYRIDINIUM SALTS
Webb, Thomas R.
, p. 3191 - 3194 (2007/10/02)
A regioselective one pot synthesis of 2-substituted pyridine derivatives from pyridine-1-oxides is described.
