99474-21-2

Basic information

• Product Name: (E)-2-(4-bromo-2-nitrophenyl)-N,N-dimethylethyleneamine
• Synonyms: (E)-2-(4-bromo-2-nitrophenyl)-N,N-dimethylethyleneamine
• CAS NO: 99474-21-2
• Molecular Weight: 271.114
• Mol File: 99474-21-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (E)-2-(4-bromo-2-nitrophenyl)-N,N-dimethylethyleneamine(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-(4-bromo-2-nitrophenyl)-N,N-dimethylethyleneamine(99474-21-2)
• EPA Substance Registry System: (E)-2-(4-bromo-2-nitrophenyl)-N,N-dimethylethyleneamine(99474-21-2)

Safety Data

• Hazardous Substances Data: 99474-21-2(Hazardous Substances Data)

Upstream product

• 60956-26-5 4-bromo-2-nitrotoluene 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 

Downstream Products

• 883149-59-5 7-bromo-3-(2,5-dimethoxyphenyl)-1H-quinolin-2-one 
• 59278-65-8 2-amino-4-bromobenzaldehyde 
• 105205-50-3 6-indolyl phenyl ketone 
• 1196-70-9 indole-6-carboxaldehyde 
• 188247-38-3 2-(4 '-Ethoxyphenyl)-6-formylindole 
• 188247-35-0 2-(4'-Ethoxyphenyl)-6-bromoindole 
• 496930-15-5 6'-bromo-N-carbobenzyloxy-L-tryptophan 
• 496930-12-2 6'-bromo-N-carbobenzyloxy-D-tryptophan 
• 496930-10-0 6'-bromo-D-tryptophan 
• 52448-17-6 (2S)-2-amino-3-(6-bromo-1H-indol-3-yl)propanoic acid 
• 207792-73-2 4'-Ethoxy-2-(4''-bromo-2''-nitrophenyl)acetophenone 
• 52415-29-9 6-bromo-1H-indole 
• 5551-12-2 4-bromo-2-nitrobenzaldehyde 

Relevant articles and documents

2-(4-Bromo-2-nitrophenyl)-1-(4-dimethylaminophenyl )-1-ethanone

The title compound, C16H15BrN2O3, is a key intermediate in the synthesis of indole-substituted Hoechst 33258 analogues. Interaction between the dimethylamino substituent and the ketone through the aromatic ring

8-SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS

Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in the treatment of autoimmunity, inflammation allergy, asthma, graft rejection, graft versus host disease, infection, sepsis, cancer and immunodeficiency.

Microwave assisted Leimgruber-Batcho reaction for the preparation of indoles, azaindoles and pyrroylquinolines

The development of enhanced conditions for Lewis acid catalysed Leimgruber-Batcho indole synthesis using microwave acceleration is described. This approach has permitted the preparation of a variety of heteroaromatic enamine intermediates in good yield and high purities. Subsequent catalytic hydrogenation reactions, under various conditions including the use of a solid-phase encapsulated catalyst, furnish the corresponding indole derivatives in good yields.